Parasites, Hosts and Diseases

The Korea Society for Parasitology and Tropical Medicine (대한기생충학·열대의학회)
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A serologically diagnosed human case of cutaneous larva migrans caused by Ancylostoma caninum

  • Kwon, In-Ho (Department of Dermatology, Seoul National University College of Medicine) ;
  • Kim, Hyung-Su (Department of Dermatology, Seoul National University College of Medicine) ;
  • Lee, Jong-Hee (Department of Dermatology, Seoul National University College of Medicine) ;
  • Choi, Min-Ho (Department of Parasitology and Tropical Medicine, Seoul National University College of Medicine) ;
  • Chai, Jong-Yil (Department of Parasitology and Tropical Medicine, Seoul National University College of Medicine) ;
  • Fukumi, Nakamura-Uchiyama (Department of Parasitology, Miyazaki Medical College) ;
  • Nawa, Yukifumi (Department of Parasitology, Miyazaki Medical College) ;
  • Cho, Kwang-Hyun (Department of Dermatology, Seoul National University College of Medicine)
  • Published : 2003.12.01
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Abstract

A 15-year-old boy, who had recently arrived back from a trip to Cambodia for a missionary camp, presented with several serpiginous thread-like skin lesions that began as small papules on the left upper extremities 2 weeks before his visit to Hospital. The skin lesions were pruritic and erythematous, and had migrated to the chest and abdomen. The histopathological findings showed only lymphocytic and eosinophilic infiltrations in the dermis of the biopsied skin lesion. The patient's serum reacted strongly to the Ancylostoma caninum antigen by an ELISA method. Therefore, he was diagnosed with cutaneous larva migrans by A. caninum. After the oral administration of albendazole and ivermectin, the skin lesions resolved without recurrence. This is the first reported case of a cutaneous larva migrans caused by Ancylostoma canimum diagnosed serologically using ELISA in Korea.

Keywords

References

  1. Alonso FF (2000) Cutaneous larva migrans. In Textbook of pediatric dermatology, Harper J, Oranje A, Neil P (eds.). p527-530, Blackwell Science, Oxford, UK.
  2. Blackwell V, Vega-Lopez F (2001) Cutaneous larva migrans: clinical features and management of 44 cases presenting in the returning traveller. Br J Dermatol 145: 434-437.
  3. Bouchaud O, Houze S, Schiemann R, et al. (2000) Cutaneous larva migrans in travelers: a prospective study, with assessment of therapy with ivermectin. Clin Infect Dis 31: 493-498.
  4. Chai JY, Han ET, Shin EH, et al. (2003) An outbreak of gnathostomiasis among Korean emigrants in Miyanmar. Am J Trop Med Hyg 69: 67-73.
  5. Chang SE, Seo CW, Choi JH, Sung KJ, Moon KC, Koh JK (1999) A case of cutaneous larva migrans showing a larva on biopsy. Korean J Dermatol 37: 547-549.
  6. Davies HD, Sakuls P, Keystone JS (1993) Creeping eruption. A review of clinical presentation and management of 60 cases presenting to a tropical disease unit. Arch Dermatol 129: 588-591.
  7. Diaz Camacho SP, Zazueta Ramos M, Ponce Torrecillas E, et al. (1998) Clinical manifestations and immunodiagnosis of gnathostomiasis in Culiacan, Mexico. Am J Trop Med Hyg 59: 908-915.
  8. Elder D, Elenitsas R, Jaworsky C, Johnson BJ (1997) Lever's histopathology of the skin. 8th ed. pp560-561, Lippincott-Raven, Philadelphia, UK.
  9. Jang IK, Lee DW, Cho BK (1995) A case of cutaneous larva migrans. Korean J Dermatol 33: 396-400.
  10. Jones WB, 2nd (1993) Cutaneous larva migrans. South Med J 86: 1311-1313.
  11. Kim JW, Kim DJ, Kim IH, Song HJ, Oh CH (1999) A case of cutaneous larva migrans. Korean J Dermatol 37: 423-426.
  12. Lim MH, Lee SC, Won YH, Chun IK (1996) A case of creeping eruption. Korean J Dermatol 34: 485-488.
  13. Lucchina LC, Wilson ME (1999) Cysticercosis and other helminthic infections. In Dermatology in general medicine, Freedberg IM, Eisen AZ, Wolff K, Austen KF, Goldsmith LA, Katz SI (eds.). p87-100, McGraw-Hill, New York, USA.
  14. Pardo RJ, Kerdel FA (1992) Parasites, arthropod, and hazardous animals of dermatologic significance. In Dermatology, Moshella SL, Hurley HJ (eds.). p2005-2009, W.B. Saunders Company, Philadelphia, USA.
  15. Stone OJ, Mullins JF (1965) Thiabendazole effectiveness in creeping eruption. Arch Dermatol 91: 427-429.
  16. Suh HS, Jee MS, Kim HH, et al. (2003) Two cases of cutaneous larva migrans. Korean J Dermatol 41: 92-95.
  17. Tada I, Araki T, Matsuda H, Araki K, Akahane H, Mimori T (1987) A study on immunodiagnosis of gnathostomiasis by ELISA and double diffusion with special reference to the antigenicity of Gnathostoma doloresi. Southeast Asian J Trop Med Public Health 18: 444-448.