Journal of the Korea Academia-Industrial cooperation Society (한국산학기술학회논문지)

The Korea Academia-Industrial cooperation Society (한국산학기술학회)
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Application of Thermal Vapor Deposition Method for MALDI-MS : Molecular Weight Determination of Insoluble Sorbitol Derivatives

열증착 시료 제작법이 적용된 MALDI 질량분석법에 의한 불용성 Sorbitol 유도체의 분자량 결정

  • 신철민 (순천향대학교 화학과) ;
  • 남해선 (순천향대학교 의공ㆍ의료정보연구원) ;
  • 김성호 (순천향대학교 의공ㆍ의료정보연구원)
  • Published : 2003.09.01
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Abstract

A thermal vapor deposition method for crystallization of insoluble analytes with matrix is established as a new sample preparation method for matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS). A mixture of mono, bis and tris(p-ethyl benzylidene) sorbitols was incorporated into microcrystals of ferulic acid, which was confirmed by confocal micrographs. Molecular masses of sorbitol derivatives were determined in this way by MALDI-MS without thermal decomposition.

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