Journal of Photoscience

한국광과학회 (Korean Society of Photoscience)
권호 표지

Regiospecific Protein Perturbation on F NMR Shifts and Photoisomerization of Fluororhodopsins. An Interpretation Based on Recent Crystal Structures of Rhodopsin

  • Colmenares, Letica U. (Department of Chemistry, University of Hawaii Honolulu) ;
  • Liu, Robert S.H. (Department of Chemistry, University of Hawaii Honolulu)
  • 발행 : 2003.04.01
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초록

Based on structural information provided by recently reported crystal structures of rhodopsin, we present rationales for the regiospecific protein perturbation on the previously reported $\^$19/F chemical shifts of the vinyl and trifluoromethylrhodopsins and their photoproducts. The crystal structures also suggest that H-bonding is a likely cause for the earlier reported regiospecific photoisomerization of the 10-fluororhodopsins. Photoisomerization was revealed by chemical shift of the photoproducts. Additionally, possible use of 3-bond F,F coupling constants for following photoisomerization of retinal-binding proteins is discussed.

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