Computed Tomographic Characteristics Of Nasal Squamous Cell Carcinoma In a Dog

개의 비강 편평상피세포종의 컴퓨터단층촬영상의 특징

  • 권정국 (서울대학교 수의과대학) ;
  • 송경진 (서울대학교 수의과대학) ;
  • 이기창 (서울대학교 수의과대학) ;
  • 이희천 (서울대학교 수의과대학) ;
  • 최민철 (서울대학교 수의과대학)
  • Published : 2003.09.01

Abstract

A female unknown aged Yorkshire terrier, weighing 3.5 kg with nasal discharge, left facial swelling and severe inflammation was referred to Veterinary Medical Teaching Hospital, Seoul National University. Radiographic findings were lytic change and soft tissue swelling of left zygomatic process and increased radiopacity of nasal cavity. In computed tomography, turbinate bone destruction was observed as well as lytic change of left zygomatic process and left maxilla indicating aggressive lesion. Then 3-dimensional reconstruction was also performed. Biopsy of tissue mass revealed it as squamous cell carcinoma. For this patient, euthanasia was performed guarded prognosis. Generally, tumors of the nasal cavity in dogs account for approximately 1 % to 2% of all neoplasms. The prevalence of these tumors increased with age and exposure to the ultraviolet. About two thirds of all nasal tumors are malignant tumors such as squamous cell carcinoma and adenocarcinoma. As these tumors of nasal cavity are locally invasive, and external beam radiotherapy is the current treatment of choice. Unfortunately, diagnosis of these tumors often occurs late in the course of disease, resulting in a poor prognosis for outcome in many patients. It is considered that computed tomography could be used as an aid modality for the exact evaluation of extend and degree of bone lysis of nasal cavity and metastasis.

Keywords

References

  1. Am J Vet Res v.37 Neoplasms of nasal passages and paranasal sinuses in domesticated animals as reported by 13 veterinary colleges Madewell,B.R.;Priester,W.A.;Gillette,E.L.;Snyder,S.P.
  2. JAAHA v.25 Canine sinonasal neoplasm : clinicopa-thological study of 285 cases Amiya,K.;Patnaik
  3. Cornell Vet v.72 Carcinoma of the nasal cavity and paranasal sinuses in dogs: descriptive epidermilogy Hayes,H.M.;Wilson,G.P.;Fraumeni,J.F.
  4. Bull cancer v.77 Modulation of neoplastic development : concepts and examples Roberfroid,M.;Preat,V.
  5. J. Am. Anim. Hosp. Assoc. v.15 Intranasal neoplasms in the dog Norris,A.M.
  6. Vet Clinic of North Am Prac v.3 Tumors of the canine nasal cavity Elsa,R.B.;Stephen J. Withrow
  7. Environ Health v.22 The environmental distribution of canine respiratory tract neoplasms. arch. Reif,J.S.;Cohen,D. https://doi.org/10.1080/00039896.1971.10665823
  8. Photochem Photobiol v.52 Molecular mechanisms of ultraviolet radiation carcinogenesis Ananthaswamy,H.N.;Pierceall,W.E. https://doi.org/10.1111/j.1751-1097.1990.tb08452.x
  9. Cancer cells v.2 Experimental models and biological mechanisms for tumor promotion Drinkwater,N.R.
  10. Vet Rad v.30 A comparison of radiographic and computed tomographic findings In 31 dogs with malignant nasal cavity tumors Donald E. Thrall;Ian,D.R.;Deborah,A.M.;Greta,L.H.;P. Jak Hoopes;Rodney
  11. JAVMA v.201 Comparison of computed tomography and 1 by malignant nasal neoplasia in dogs Richard,D.P.;Elsa,R.B.;Richard,A.L.
  12. JAAHA v.31 Squamous cell carcinoma of the canine nasal planum : eight Cases (1988-1994) Kenita,S.R.;R.Gayman Helman;Michael,A.W.