Animal cells and systems

The Korean Society for Integrative Biology (한국통합생물학회)
권호 표지

Effect of Lambda Cyhalothrin (Pyrethroid) and Monocrotophos (Organophosphate) on Cholinesterase Activity in Liver, Kidney and Brain of Rana cyanophlyctis

  • Khan, M.Zaheer (Department of Zoology(Wildlife ＆ Fisheries), University of Karachi) ;
  • Zaheer, Maria (Department of Zoology(Wildlife ＆ Fisheries), University of Karachi) ;
  • Fatima, Farina (Department of Zoology(Wildlife ＆ Fisheries), University of Karachi)
  • Published : 2003.06.01
Download PDF
⟨ Previous Next ⟩

Abstract

The present studies investigate the induced effects of two pesticides lambda cyhalothrin (pyrethroid) and monocrotophos (organophosphate) on Rana cyanophlyctis (common skittering frog). Two different concentrations i.e. 0.1 and 1％ were used and cholinesterase activity was observed in liver, kidney and brain of these frogs. It was decreased upto 34.6 and 46.3％ in liver, 25.08 and 57.1％ in kidney and 31.64 and 50.7％ in brain under the effect of lambda cyhalothrin. In the case of monocrotophos treatment, cholinesterase decreased upto 37.7 and 57.7％ in liver,57.5 and 67.5％ in kidney and 47.6 and 65.9％ in brain, respectively.

Keywords

References

  1. Bradbury SP, and Coat J.R (1982) Toxicity of fenvalerate to bobwhite quail (Colinus virginianus) including brain and liver residuce associated with mortality. J. Toxicol. Environ. Health 10: 307-319 https://doi.org/10.1080/15287398209530253
  2. Berril MS, Bertram A, Wilson S, Louis S, Brigham, and Stromberg C (1993) Lethal and sublethal impacts of pyrethroid insecticides on amphibian embroys and tadpoles. Environ. Toxicol. Chem. 12(3): 525-539 https://doi.org/10.1002/etc.5620120313
  3. Balasumdaram K, and Selvarajan VR (1990) Inhibition of acetylcholinesterase in hte central nervous system of Rana tigrina by an organophosphate. J. Biochem. Toxicol. 5(5): 65-66 https://doi.org/10.1002/jbt.2570050110
  4. Burn JD, and Leighton FA (1996) Further studies of brain cholinesterase: Cholinergic receptors rations in the diagnosis of acute lethal poisoning of birds by anticholinesterase pesticides. J. Wildlife Dis. 32(2) 216-224 https://doi.org/10.7589/0090-3558-32.2.216
  5. Bishop CA, Collin B, Mineau P, Burgees NM, Red WF, and Risley C (2000) Reproduction activity of nesting birds in pesticide sprayed apple orchards in Southern Ontario, Canada. Environ. Toxicol. Chem. 19(3): 588-599
  6. Burgees NM, Hunt KA, Bishop C, and Weseloh DV (1999) Cholinesterase inhibition in tree swallow (Tachycineta and eastern blue bird Sialia sialis) exposed bicolor to organophosphorus insecticides in apple orchards in Ontario Canada. Environ. Toxicol. Chem. 18(4): 708-716 https://doi.org/10.1897/1551-5028(1999)018<0708:CIITST>2.3.CO;2
  7. Bridges CM, and Boone MD (2003) The interactive effects of UV-B and insecticide exposure on tadpole survival, growth and development. Biol. Conservation 113: 49-54 https://doi.org/10.1016/S0006-3207(02)00348-8
  8. Clark DR Jr, Spann JW, and Bunck CM (1990) Dicofoi (Kelthane) induced eggshell thinning in captive American kestrels. Environ. Toxicol. Chem. 9: 1063-1069 https://doi.org/10.1002/etc.5620090813
  9. Clark DR Jr., Flickinger EL, White DH, Hothem RL, and Belisle AA (1995) Dicofol and DDT residuces in lizard carcasses and bird eggs from Texas, Florida and California. Bull. Environ. Contam. Toxicol. 54: 817-824 https://doi.org/10.1007/BF00197964
  10. Cooper K (1991) Effects of pesticides on wildlite, Hanbook of Pesticides Toxicology. Vol. 1. General Principles. Academic Press, New York, USA, pp. 463-496
  11. Carey C, and Bryant CJ (1995) Possible interrelations among environmental toxicants, amphibian development, and decline of amphibian populations. Environ. Health Perspect. 103 (supp. 4): 13-17
  12. Flickinger EL, Juenger G, Roffe TJ, Smith MR, and Irwin RJ (1991) Poisoning of Canada geese in Texas by parathion sprayed for control of Russian wheat applied. J. Wildlife Dis. 27(2): 265-268 https://doi.org/10.7589/0090-3558-27.2.265
  13. Carcelon DK, and Thomas NJ (1997) DDE poisoning in adult bald eagle. J. Wildlife Dis. 33(2): 299-303 https://doi.org/10.7589/0090-3558-33.2.299
  14. Gilbertson MK, Haffner GD, Drouillard KG, Albert A, and Dixon B (2003) Immunosuppression in the northern leopard frog (Rana pipiens) induced by pesticides exposure. Environ. Toxicol. Chem. 22(1): 101-110 https://doi.org/10.1897/1551-5028(2003)022<0101:IITNLF>2.0.CO;2
  15. Hill EF, and Fleming WJ (1982) Anticholinesterase poisoning of birds; field monitoring and diagnosis of acute poisoning. Environ. Toxicol. Chem. 1: 27 https://doi.org/10.1002/etc.5620010105
  16. Knedel M, and Boetteger R (1967) Kinetic method for determination of pseudocholinesterase (acylcholine acylhydrolase) activity. Klin. Wochenschr. 45(6): 325-327 https://doi.org/10.1007/BF01747115
  17. Kegley S, Neumeister L, and Martin T (1999) Disrupting the balance. Ecological impacts of pesticides in California. Pesticide Action Network, pp. 99
  18. Khan MZ (2000) Determination of induced effect in Agama against permethrin and neem fractions and their effect on proteinic and enzymatic pattern, Ph.D. thesis, Department of Zoology, University of Karachi, Karachi
  19. Khan MZ (2002) Comparison of induced effect of pyrethroid (Permethrin) with phytopesticide (Biosal) on cholinesterase activity against lizard Calotes versicolor Daudin (Agamidae). J. Nat. His. Wildlife. 1: 15-20
  20. Khan MZ, and Fatima F (2002) Comparison of induced effect of pyrethroid (cypermethrin) with organophosphate (malathion) of GOT and GPT in liver, kidney and brain of Calotes versicolor Daudin (Agamidae: Reptilia). Online J. Biol. Sci. 2(6): 408-410 https://doi.org/10.3923/jbs.2002.408.410
  21. Khan MZ, Naqvi SNH, Khan MF, Rahila T, Ahmad I, and Farina F (2002 a) Induced effect of Biosal on GOT and GPT in wildlife species of Agama lizard Calotes versicolor. Pakistan J. Bio. Sci. 4: 611-612
  22. Khan MZ, Erum ZS, Ahmad I, and Fatima F (2002 b) Effect of agricultural pesticide permethrin on protein contents in liver and kidney of lizard Calotes versicolor in comparison to frog Rana tigrina. Bull. Pure and Appl. Sci. 21 A(2): 93-97
  23. Khan MZ, Fatima F, and Ahmad I (2002 c) Effect of Cypermethrin on protein contents in lizard Calotes versicolor in comparison to that in frog Rana tigrina. Online J. Biol. Sci. 2(12): 780-781 https://doi.org/10.3923/jbs.2002.780.781
  24. Khan MZ, Naqui SNH, Khan MF, Tabassum R, Ahmad I, Fatima F, Tariq RM (2003a) Determination of induced effect of phytopesticide Biosal (Neem based formulation) on cholinesterase activity and protein contents in kidney and liver of Calotes versicolor Daudin. J. Exp. Zool. India. 6(1): 175-179
  25. Khan MZ, Tabassum R, Erum ZS, Farhana T, Khan MF, Naqvi SNH, and Ahmad I (2003b) Effect of cypermethrin and permethrin on cholinesterase activity and protein contents in Rana tigrina (Amphibia), Turkish J. Zool. (in press)
  26. Mineau P (1993) The hazard of carbofuran to birds and other vertebrate wildlife, Technical Report Series No. 177, Canadian Wildlife Service
  27. Martin RE (2000) Other aquatic life of economic significance: Frogs and frog legs, Marine and freshwater products handbook. Martin, EP.,Flick, GJJ., and Davis, LM. (ed), Lancaster, Technomic Pub. Co. Inc. 279-287
  28. Nizam S (1993) Effect of allelochemicals and against 3rd instar larvae of Musca domestica L. (Malir strain), Ph.D. thesis, Departement of Zoology, University of Karachi, Karachi
  29. O'Hara TM, Krahn MM, Boyd D, Becker PR, and Philo LM (1999) Organochlorine contaminant levles in Eskimo harvested bowhead whales of Arctic Alaska. J. Wildlife Dis. 35(4): 741-752 https://doi.org/10.1897/1551-5028(2000)019<1317:MWBETA>2.3.CO;2
  30. Parsons KC, Matz AC., Hooper MJ, and Pokras MA (2000) Monitorinh eading bird exposure to agricultural chemicals using serum cholinesterase activity. Environ. Toxicol. Chem. 19(5): 1317-1323 https://doi.org/10.1002/etc.5620190514
  31. Pauli BD, and Money S (2000) Ecotoxicology of pesticides in reptiles. Society of Environmental Toxiocology and Chemistry. 269-324
  32. Shakoori AR, and Ahmad MS (1973) Studies on the liver of chicken Gallus domasticus. Liver growth and nucleic acid content. Pakistan J. Zool. 5: 111-117
  33. Taylor SK, Williams ES, and Mills KW (1999) Effects of malathion on disease susceptibility in Woodhouse's toads. J. Wildlife Dis. 35(3): 536-541 https://doi.org/10.7589/0090-3558-35.3.536