Korean Journal of Community Nutrition (대한지역사회영양학회지)

The Korean Society of Community Nutrition (대한지역사회영양학회)
권호 표지

The Effects of Programmed Dietary System of a Mixture of Natural Supplements on the Composition, Serum Lipids and the Leptin Levels

천연 소재 조성물의 3.3.3 System Diet Program이 각 단계별 신체조성, 혈청 지질 개선 효과 및 Leptin 수준에 미치는 영향에 관한 연구

  • Published : 2003.06.01
Download PDF
⟨ Previous Next ⟩

Abstract

This study was to investigate the effects of a silk peptide, and prune and raspberry mixture on the body fat, serum lipid composition and fat distribution in Korean women during the time they received these supplements. During the 4 month period of this research (June to October, 2002), 75 women (average age 22.9 yr) were selected as subjects. Their nutrient intake was investigated by use of a questionnaire and the 24-hour recall method. Antropometric assessments of the subjects were investigated by using the SBIA Method (Segmental Bioimpedance Assay, Inbody 3.0). The results were as follows: their mean body weight was 59.3 kg, their mean body height was 161.7 cm and their mean Basal Metabolic Indices (BMI) was 22.7. The status of their dietary fiber intake significantly increased (p < 0.05) after use of the supplements. Their body fat significantly decreased following the $3^{rd}$ stage of supplementation (p < 0.05), and their percent of body fat signiflcantly decreased after supplementation (p < 0.05). Their triceps and suprailiac circumference significantly decreased following the $3^{rd}$ stage of supplementation (p < 0.05). Their waist circumferences and waist-hip ratios (WHR) significantly decreased after both the $2^{nd}$and $3^{rd}$ stage of supplementation (p < 0.05). Their total cholesterol significantly decreased following the $3^{rd}$ stage of supplementation, as compared to their baseline results and those obtained following the 1$^{st}$ stage of supplementation (p < 0.05). Their LDL-cholesterol and LDL / HDL ratios significantly decreased following the $3^{rd}$ stage of supplementation, as compared to their baseline results and those obtained following the 1$^{st}$ stage of supplementation (p < 0.05). Their 4-HNE and total antioxidant statuses significantly decreased following the $2^{nd}$ and $3^{rd}$stage of supplementation, as compared to their baseline results and those obtained following the $1^{st}$ stage of supplementation (p <0.05). Their $2^{nd}$ stage supplementation results were significantly negatively correlated with their triceps measurements and WHR (p < 0.05). Their $3^{rd}$stage supplementation results were significantly negatively correlated with their anterior thigh measurements (p < 0.05). The above results show that prune, raspberry, silk peptide and dietary fiber supplementation to a routine diet improves body fat distribution, total cholesterol, and triglyceride levels. The decrease of abdominal fat and WHR were especially noteworthy. This implies a decrease of risk factors. (Korean J Community Nutrition 8(3) : 356~367, 2003)003)

Keywords

References

  1. Ahren B, Mansson S, Gingerich RL, Havel PJ (1997): Regulationof plasma leptin in mice: influence of age, high-fat diet, and fastng. Am J Physiol 273: 113-120
  2. Ancos B, Gonzalez EM (2000): Ellagic acid, vitamin C, and total phenolic contents and radical scavenging capacity affected by freezing and frozen storage in raspberry fruit. J Agric Food Chem 48 (10): 4565-4570
  3. Ashley FW Jr, Kannel WB (1974): Realtion of weight change to changes in atherogenic traits: The Framingham study. J Chronic Dis 27: 103-111 https://doi.org/10.1016/0021-9681(74)90079-4
  4. Blumenthal M (1998): The complete commission german monographs. American botanical council, Texas, USA
  5. Borum PR (1987): Plasma carnitine compartment and red blood cell carnitine compartment of healthy adults. American J of Clinical Nutrition 46: 437-441
  6. BS Gould, JF Woessner (1957): Biosynthesis of collagen. The influ-ence of ascorbic acid on the proline, hydroxyproline, glycine and collagen content of regenerating guinea pig skin. J Bioi Chem, pp.226-289
  7. Cameron E, Pauling L (1976): Supplemental ascorbate in the suppor-tive treatment of cancer: prolongation of survival times in ter-minal human cancer. Proceedings of the National Academy of Sciences 73: 3685-3689 https://doi.org/10.1073/pnas.73.10.3685
  8. Castelli WP, Wilson PW, Levy D, Anderson K (1990): Serum lipids and risk of coronary artery diseases. Atheroscl Rev 21 (7) : 222-229
  9. Choi JW, Lee KM, Kim HJ, Kim SH, Kim HS, Ro JS, Oh KW, Lee KS (2002) : The effects of dried orange peel compound intaking and exercise training on the physique, body fat, and concentration of blood lipid in obese women. Kor J Pharmacogn 33 (1): 57-63
  10. Choi SK, Ahn YN (1996): The effects of carnitine administration on energy substrate utilization and all out time during exercise. Korean J Physical Education 35 (4): 218-229
  11. Clark PA, Martin JH (1993): Selection of Bifidobacteria for use dietary adjuncts in cultured dairy food: Tolerance to simulated pH of human stomachs. Cult Dairy Prod J, pp.11-14
  12. Colker MC, Kalman DS, Torima GC, Perlis T, Street C (1999): Effects of citrus aurantium extract, caffeine, and St. John's wrot on body fat loss, lipid levels, and mood states in overweight healthy adults. Current Therapeutic Research 60 (3): 145-153
  13. Ebestein LH, Wing RR, Valoski A (1995): Childgool obesity. Pediatr Clin North Am 32: 363-379
  14. Englyst HN, Cummings JH (1985): Digestion of polysaccharides of some cereal foods in human small intestine. Am J Clin Nutr 42: 778-787 https://doi.org/10.1093/ajcn/42.5.778
  15. Esterbauer K, Cheesman H (1990): Methods Enzymol 186: 407-421
  16. Friedewald WT, Levy RL, Fredrickson DS (1972): Estimation of the concentration of low density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge, clinical chemistry. Clini Chem 18: 499
  17. Havel PJ, Uriu-Hare JY, Lui T, Stanhope KL, Stern JS, Keen CL, Ahren B (1998): Marked and rapid decreases of circulating leptin in streptozotocin diabetic rats: reversal by insulin. Am J Physiol 274: 1482-1491
  18. Huh KB (1990) : Cause of obesity. Korean J Nutrition 23: 333-336
  19. Janero DR (1990): Malondialdehyde and thiobar-biruric acid reac-tivity as diagnostic indices of lipid peroxidation and peroxidative tissue injury. Free Rad Biol Med 9: 515-540
  20. Jeong KA (1995): Effect of Cereals on Lipid Concentration of Liver and Serum in the Rats. Korean J Nutrition 28 (1): 11-13
  21. Joo KJ (1978): Studies on chemical composition of raspberry. Korean J Nutrition 11 (3): 21-24
  22. Katai K (1942): Trace components in mulberry leaves. J Chem Soc Jpn 18: 379-383
  23. Kayano S, Kikuzaki H, Fukutsuka N, Mitani T, Nakatani N (2002): Antioxidant activity of prune (Prunus domestica L.) constituents and a new synergist. J Agric Food Chem 50 (13): 3708-3712
  24. Kim JH, Ryu SP, Lee SC (1998): Effects of acute administration of carnitine on energy utilization in trained rats. Korean J Exercise Nutrition 2 (2): 15-24
  25. Kim JH, Wang SG (1997): Effects of mugwort, dried orange peel and duchung on lipid metabolism in hyperlipidemia rats. Korean J Nutrition 30(8): 895-903
  26. Kim MJ, Lee SS (1995): The Effect of Dietary Fiber on the Serum Lipid Level and Bowel Function in Rats. Korean J Nutrition 28 (1) : 23-32
  27. Kim SK, Kim YS, Kim AJ, Kim SY (1998): Effect of weight reductionon supplementation of mulberry leaves. Abstract presented at the 44th The Korean society of Food Science and Nutrition Conference, pp.147
  28. Kim SK, Kim SY, Kim HJ, Kim AJ (2001): The effect of mulberry-leaf extract on the body fat accumulation in obese fa/fa male zucker rats. J Korean Soc Food Sci Nutr 30 (3) : 516-520
  29. Kim SY, Lee WC, Kim HB, Kim AJ, Kim SK (1998): Antigyperlipidemic effects of methanol extracts from mulberry leaves in cho-lesterol- induced hyperlipidemia rats. J Korean Soc Food Sci Nutr 27(6): 1217-1222
  30. Kim YS (1990) : Classification and estimation of obesity. Korean J Nutrition 23: 337-340
  31. Kondo Y (1957): Trace constituents of mulberry leaves. Nippon San-shigaku Zasshi 26: 349-353
  32. Lee HK (1990): Diseases related to obesity. Korean J Nutrition 23: 341-346
  33. Lee SH, Lee CJ, Choi YJ (2001): Antitumor activites and the lowering effect on the serum cholesterol level of natural silk hydrolysates. pp. 240, Abstract P8-58 presented at 67th Annual Meeting of the Korean Society of Food Science and Technology
  34. Lee SH, Lee CJ, Choi YJ, Ko KH (2001): Components and antitumor activities of silk amino acid, pp.85, Abstract presented at 2001 Annual Meeting of the Korean Nutrition Society
  35. Lee SH, Cho BN, Hyun CK, Jew SS (2002): Physiological, functional Characteristics of silk peptide: Antioxidant effect and immune function. Food Science and Industry 35 (4) : 57-62
  36. Lee HS, Kim SY, Lee WC, Lee SD, Moon JY, Ryu KS (2000): Effects of dietary mulberry leaf powder on gastrointestinal function of rat. J Korean Soc Food Sci Nutr 29 (5) : 865-869
  37. Lee HS, Jeon HJ, Lee SD, Moon JY, Kim AJ, Ryu KS (2001): Effect of dietary mulberry leaf on the composition of intestinal micro-flora in SD rats. Korean J Food Technol 33 (2): 252-255
  38. Lee HY (1997): A study on effects of aloe added diet control program S-28 on obese women. J Korean Soc Study Obesity 6 (1) : 75-84
  39. Linner JG, Buescher ES, Siemsen DW, Dratz EA, Quinn MT, Jesaitis AJ (I992) : Electron microscopic immunocytochemical co-localiza-tion of superoxide generating components and targets in resting and stimulated human neutrophils. pp.277-281, CRC Press. Boca Raton
  40. Liu M, Li XQ, Weber C, Lee CY, Brown J, Liu RH (2002): Antioxidant and antiproliferative activities of raspberries. J Agric Food Chem 50 (10): 2926-2930
  41. Mariko H (2002): presented at the Experimental Biology Conference. April 2
  42. Miller NJ, Rice-Evan C, Davis MJ, Gopinathan V. Milner A (1993): A novel method for measuring antioxidant capacity and its application to monitoring the antioxidant status in premature neonates. Clin Sci 84: 407-412 https://doi.org/10.1042/cs0840407
  43. Moon HN, Hong SJ, Suh SJ (1992): The Prevalence of Obesity in Children and Adolescents. Korean J Nutrition 25: 413-418
  44. Moon JS, Oh SW, Jeon HI, Cho BR, Heo BN (2000): The factors re-lated to serum total cholsterol/high-density lipiprotein (HDL) cho-lesterol ratio in healthy adults. J Korean Acad Fam Med 21 (2): 144-152
  45. Moon SJ, Kim HS, Kim JH, Park KS, Yoo YH (1995): The Effect of Weight Control on Obese Women. Korean J Nutrition 28: 759-770
  46. Nakatani N, Kayano S, Kikuzaki H, Sumino K, Katagiri K, Mitani T (2000): Identification, quantitative determination, and antioxi-dative activities of chlorogenic acid isomers in prune (Prunus domestica L.). J Agric Food Chem 48 (11): 5512-5516 https://doi.org/10.1021/jf000422s
  47. Park KJ, Hong SY, Do MS, Hyun CK (2002): Stimulation of Insulin Secretion by Silk Fibroin Hydrolysate in Streptozotocin: induced Diabetic Rats and db/db Mice. Kor J Pharmacogn 33 (1) : 21-28
  48. Polloick ML, Jacson AS (1994): Research progress in validation of clinical methods of assessing body composition. Med Sci Sports Exerc 16: 606-613
  49. Proteggente AR, Pannala AS, Paganga G, Van Buren L, Wagner E, Wiseman S, Van De Put F, Dacombe C, Rice- Evans CA (2002): The antioxidant activity of regularly consumed fruit and veget-ables reflects their phenolic and vitamin C composition. Free Rudie Res 36 (2): 217-233
  50. Sayama K, Lin S, Zheng G, Oguni I (2000): Effects of green tea on growth, food utilization and lipid metabolism in mice. In Vivo 14(4): 481-484
  51. Schneeman BO (1987): Soluble vs insoluble fiber-different physiological responses. Food Technol 41: 81-82
  52. Stacewicz M, Bowen PE, Hussain EA, Eamayanti-Wood BI, Farns-worth NR (2001): hemical composition and potential health effects of prunes. Crit Rev Food Sci Nutr 41 (4): 251-286
  53. T Ryan, JM Wilkinson, HMA Cavanagh (2001): Antibacterial activity of raspberry cordial in vitro. Research in Veterinary Science 71: 1-5
  54. The Korean Nutrition Society (2000): Recommended dietary allo-wances for Koreans, pp.24-25, 7th ed. Chungang Publisher
  55. Van Itallile TB (1978): Dietary fiber and obesity. Am J Clin Nutr 31: 123-128
  56. Wallach J (1998): Interpretation of diagnostic test 6th ed. pp.477-485, Little Brown and Company, Boston