한국축산식품학회지 (Food Science of Animal Resources)

  • 제23권1호
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  • Pages.75-79
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  • 2003
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  • 2636-0772(pISSN)
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  • 2636-0780(eISSN)
한국축산식품학회 (Korean Society for Food Science of Animal Resources)
권호 표지

몽고 마유에 함유된 사이토카인에 관한 연구

A Study on Cytokines in the Mongolia Mare's Milk

  • 발행 : 2003.03.01
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초록

본 연구는 몽고 마유에서 pro-inflammatory cytokine(IL-l$\beta$, IL-6, TNF-a, IL-18)과 IL-1 receptor accessory를 Western blotting방법으로 확인하여 기능성 식품과 의약품 소재로 이 용하기 위한 기초 자료를 얻고자 실시하였다. 몽고 마유의 4개군 모두에서 IL-1, TNF-a가 17 kD에서 확인되었다. IL-18은 6~7 kD에서 확인할 수 있었다. 그리고, IL-1 receptor accessory를 55 kD에서 확인하였다. 그러나 탈지분유(Difco) 에서는 IL-l$\beta$, TNF-a를 확인할 수 없었으나, IL-6는 탈지분유(Difco) 및 몽고 마유에서 모두 60 kD에서 확인하였다. 이 와 같이 몽고 마유는 다양한 cytokine을 함유하고 있어서 기능성 식품 및 의약품 소재로 이용가치가 있다고 사료된다.

This study was carried out to detect the pro-inflammatory cytokines(IL-1, IL-6, TNF-a, IL-18) and IL-1 receptor accessory in mongolia mare's milk by western blotting. IL-1 and TNF-a were detected in 4 samples of mare's milk Proteins of 6 kD and 7 kD were bound to specific antibody against hIL-18. But, IL-l and TNF-a were not detectable in Difco skim milk IL-6 like factor of 60 kD was detected in both Difco skim milk and mare's milk. Also, IL-1 receptor accessory of 55 kD was detected in the mongolia mare's milk.

키워드

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