Journal of Nutrition and Health

The Korean Nutrition Society (한국영양학회)
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Effects of Nutrient Intake, Bone Mineral Density and Bone Mineral Content in Ovariectomized Women

난소 절제 여성의 영양소 섭취 상태가 골밀도 및 골무기질 함량에 미치는 영향

  • Published : 2003.03.01
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Abstract

This study investigated associations between nutrient intake, lumbar bone mineral density (BMD) , and bone mineral content (BMC) among 33 ovariectomized women (mean age =47.2 y) . Forty-five premenopausal women participated as a control group. The BMD and BMC of the lumbar spine (L$_2$-L$_4$) were measured by dual energy x-ray absorptiometry. Nutrient intake was estimated by the convenient method and a quantitative food frequency questionnaire was designed for this study that included the most commonly consumed foods sources of calcium. Participants were asked to identify all daily physical activities, and the number of hours per activity. The participants were also grouped by calcium intake. The total calcium intake of all participants was estimated by dietary calcium intake and then the subjects were divided into quartiles to assess the lumbar BMD and BMC of the highest quartile and the lowest quartile of calcium intake. The ovariectomized women consumed 602 mg/d of calcium which is 86% of RDA. There were significant differences in lumbar BMD and BMC between control and ovariectomized group. Within ovariectomized group the highest quartile calcium intake group had significantly greater lumbar bone mineral density and bone mineral content than the lowest quartile calcium intake group. Correlation analysis revealed that the ALP was positively associated with calcium index in control women, while ALP was positively associated with energy intake in ovariectomized women. And body weight was positively correlated with the spinal BMD and BMC in all women. The spinal BMD was negatively associated with menarche age, number of child, and the age of last child delivery, and age in control women. However, neither menarche age nor the age of last child delivery were associated with both spinal BMD in ovariectomized women. These results confirmed that ovariectomized and low calcium intake is associated with poor bone mineral density. Energy and calcium intake and adequate body weight should be recommended in ovariectomized women to prevent osteoporosis.

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References

  1. Yearbook of public health and welfare statistics Department of public health and welfare
  2. Am J Med v.91 no.SUP. Bone mass measurements in diagnosis and assessment of therapy Wasnich RD
  3. J Nutr v.126 Symposium: Nutritional advances in human bone metabolism. Introduction Anderson JJB
  4. Korean J Community Nutrition v.7 no.1 A study of nutrient intake and serum levels of osteocalcin, Ca, P, and Mg and their correlation to bone mineral density in Korean postmenopausal women residing in rural areas Sung CJ;Choi YH;Kim MH;Choi SH;Cho KO
  5. Korean J Nutr v.33 no.3 A study on the factors affecting bone mineral density in adult women-based on the mothers of elementary school students Kim KR;Kim KH;Lee EK;Lee SS
  6. Korean J Nutr v.32 no.2 A study on the bone mineral density and related factors in Korean postmenopausal women Lee HJ;Lee HO
  7. The Korean Nutrition Society(7th Revision) Recommended Dietary Allowances for Koreans
  8. Am J Clin Nutr v.72 no.3 Isoflavone-rich soy protein isolate attenuates bone loss in the lumbar spine of perimenopausal women Alekel, DL;St Germain A;Peterson CT;Hanson KB;Stewart JW;Toda T
  9. Am J Clin Nutr v.68 no.SUP. Soy protein and isoflavons: their effects on blood lipids and bone density in postmenopausal women Potter SM;Baum JA;Teng H;Stillman RJ;Erdman JW Rr
  10. Science v.241 Evidence of estogen receptors in normal human osteoblast like cells Eriksen EF;Colvard DS;Berg NJ https://doi.org/10.1126/science.3388021
  11. J Bone Miner Res v.13 Long-term effects of calcium supplementation on serum parathyroid hormone level, bone turnover, and bone loss in elderly women Riggs BL;O'Fallon WM;Muhs J;O'Connor MK;Kumar R;Melton LJ III https://doi.org/10.1359/jbmr.1998.13.2.168
  12. Younseinonchong Application of convenient method for the study of nutritional status of middle aged Korean women Moon SJ;Lee KY;Kim SY
  13. Anal Biochem v.18 An improved automated procedure for the determination of calcium in biological specimens Gitelman HJ https://doi.org/10.1016/0003-2697(67)90110-8
  14. Biochem Biophys Acta v.320 The determination of inorganic orthophosphate in biological system Atkinson A;Gatenby AD;Lowe AG https://doi.org/10.1016/0304-4165(73)90178-5
  15. Clin Chem v.11 An automated para-nitrophenylphosphate serum alkaline phosphatase procedure for the autoanalyzer Mogenstern S;Kessler G;Auerbach J;Flor RV;Klein B
  16. Korean J Community Nutrition v.5 no.3 1998 National health and nutrition survey report-Nutrition survey Shin AJ
  17. Korean J Nutr v.35 no.4 2002 Effects of nutrient and exercise on bone mineral density and bone mineral content in premenopausal women Choi MJ
  18. Clin Orthop v.165 Aging bone loss Mazess RB
  19. N Engl J Med v.311 Relative contributions of aging and estrogen deficiency to postmenopausal bone loss Richelson LS;Wahner HW;Melton LJ III;Giggs BL https://doi.org/10.1056/NEJM198411153112002
  20. J Nutr v.110 Influence of adult age on the skeletal response to phosphate and estrogen in rats Draper HH;Bell RR;Shin KS
  21. Am J Med v.98 no.2A The burden of osteoporsis Lindasy R
  22. Korean J Nutr v.25 no.2 Nutrient intake and bone mineral density in Korean premenopausal women Lee JH;Choi MS;Paik IK;Moon SJ;Lim SK;Ahn KJ;Song YD;Lee HC;Huh KB
  23. Korean J Nutr v.33 A study on the factors affecting bone mineral density in adult women-based on the mothers of elementary school students Kim KR;Kim KH;Lee EK Lee SS
  24. Korean J Nutr v.31 no.9 The relationship between food habit , nutrient intakes and bone mineral density and bone mineral content in adult women Choi MJ;Jung YJ
  25. Korean J Nutr v.29 no.1 Effects of dietary calcium, protein and phosphorus intakes on bone mineral density in Korean premenopausal women Oh JJ;Hong ES;Baik IK;Lee HS;Lim HS
  26. J East Asian Society of Dietary Life v.4 no.3 The relationship between bone mineral density and the environmental factors in Korean girls(I) Choi MJ
  27. Am J Clin Nutr v.54 Calcium supplementation and bone loss: A review of controled clinical trials Dawson-Hguhes B
  28. JAMA v.268 Bone gain in young adult women Recker RR;Davies KM;Hinders SM;Heaney RP;Strgman MR;Kimmel DB https://doi.org/10.1001/jama.268.17.2403
  29. Am J Clin Nutr v.65 Nutritional influences on bone mineral density: a cross-sectional study in premenopausal women New SA;Bolton-Smith C;Grubb DA;Reid DM
  30. Am J Clin Nutr v.54 Influence of calcium intake and growth indexes on vetebral bone mineral density in young females Sentipal JM;Wardlaw GM;Mahan J;Matkovic V
  31. J Bone Miner Res v.2 no.SUP.1 Bone mineral density of the spine Mazess RB;Barden H;Green G
  32. Am J Clin Nutr v.54 no.SUP. Calcium supplementation and bone loss: a review of controlled clinical trials Dawson-Hughes B
  33. N Engl J Med v.328 Effect of calcium supplementation on bone loss in postmenopausal women Reid IR;Ames RW;Evans MC;Gamble GD;Sharpe SJ https://doi.org/10.1056/NEJM199302183280702
  34. Am J coll Nutr v.19 Calcium, dairy products and osteoporosis Heaney RP
  35. Korean J Nutr v.35 no.7 Nutritional factors related to bone mineral density in the different age groups of Korean Women Yh Ch;Lee JS;Lee LH;Kim SH;Lee SS;Jung IK
  36. J Bone Miner Res v.8 Effects of weight and body mass index on bone mineral density in men and women: the Framingham study Felson DT;Zhang Y;Hannan MT;Anderson JJ https://doi.org/10.1002/jbmr.5650080507