The Journal of Korean Physical Therapy
- 제15권2호
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- Pages.146-156
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- 2003
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- 1229-0475(pISSN)
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- 2287-156X(eISSN)
쥐의 적출 대동맥에 자외선 조사로 유발된 photorelaxation 기작의 생리학적 특성
Physiological characterization of mechanism on UV light-induced photorelaxation in isolated rat aorta
- Lee Han-Ki (Department of Physical Therapy, Masan College) ;
- Hong Yong-geun (Department of Physical Therapy, Masan College) ;
- Kim Kyung (Department of Physical Therapy, Seoul Health College)
- 발행 : 2003.06.01
초록
Isolated rat thoracic aorta which is pharmacologically precontracted by phenylephrine induces photorelaxation when exposed to long wave length UV-light. The aim of the present study was to characterize the mechanism of UV-light induced by photorelaxation in the rat aorta. 1. UV light relaxed both endothelium-intact and -denuded rat aortic rings contracted by phenylephrine. The magnitude of relaxation on UV light was dependent on the exposure time and slightly greatly in endothelium-denuded rings than in endothelium-intact preparations. 2. L-NAME (10 nM - 100
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