References
- Al-Harbi, M. M., Al-Gharably, N. M., Al-Shabanah, O. A., Al-Bekairi, A. M., Osman, A. M. and Tawfik, H. N. (1992)Prevention of doxorubicin-induced myocardial andhaematological toxicities in rats by the iron chelatordesferrioxamine. Cancer Chemother. Pharmacol. 31, 200-204. https://doi.org/10.1007/BF00685548
- Al-Shabanah, O., Mansour, M., El-Kashef, H. and Al-Bekair, A.(1998a) Captopril ameliorates myocardial and hematologicaltoxicities induced by adriamycin. Biochem. Mol. Biol. Int. 45,419-427.
- Al-Shabanah, O. A., Badary, O. A., Nagi, M. N., Al-Garably, N.,Al-Rikabi, A. and Al-Bekairi, A. M. (1998b) Thymoquinoneprotects against doxorubicin-induced cardiotoxicity withoutcompromising its antitumor activity. J. Exp. Clin. Cancer Res.17, 193-198.
- Blum, R. H. and Carter, S. K. (1974) Adriamycin. A newanticancer drug with significant clinical activity. Ann. Intern.Med. 80, 249-259. https://doi.org/10.7326/0003-4819-80-2-249
- Buja, L. M., Ferrans, V. J., Mayer, R. J., Roberts, W. C. andHenderson, E. S. (1973) Cardiac ultrastructural changesinduced by doxorubicin therapy. Cancer 32, 771-788. https://doi.org/10.1002/1097-0142(197310)32:4<771::AID-CNCR2820320407>3.0.CO;2-A
- Choi, B. M., Pae, H. O., Jang, S. I., Kim, Y. M. and Chung, H. T.(2002) Nitric oxide as a pro-apoptotic as well as anti-apoptoticmodulator J. Biochem. Mol. Biol. 35, 116-126. https://doi.org/10.5483/BMBRep.2002.35.1.116
- Corbett, J. A., Tilton, R. G., Chang, K., Hasan, K. S., Ido, Y.,Wang, J. I., Sweetland, M. A., Lancaster, J. R., Williamson, J.R. and McDaniel, M. L. (1992) Aminoguanidine a novelinhibitor of nitric oxide formation prevents diabetic vasculardysfunction. Diabetes 41, 552-556. https://doi.org/10.2337/diabetes.41.4.552
- de-Belder, A. J. and Radomski, M. W. (1994) Nitric oxide in theclinical arena. J. Hypertension 12, 617-624.
- Doroshow, J. H., Looker, G. Y., Ifrim, I. and Myers, C. E. (1981)Prevention of doxorubicin cardiac toxicity in the mouse by N-acetylcysteine.J. Clin. Invest. 68, 1053-1064. https://doi.org/10.1172/JCI110328
- Doroshow, J. H. (1983) Effect of anthracyclin antibiotics onoxygen radical formation in rat heart. Cancer Res. 43, 460-472.
- Ellman, G. L. (1959) Tissue sulfahydryl groups. Arch. Biochem.Biophys. 82, 70-77. https://doi.org/10.1016/0003-9861(59)90090-6
-
Gruber, W. (1978) Inhibition of creatine kinase activity by
$Ca^{2+}$ and reversing effect of EDTA. Clin. Chem. 24, 177-184. -
Higgins, C. P., Baehner, R. L., McCallister, J. and Boxer, L. A.(1978) Polymorph nuclear leukocytes species difference in thedisposal of hydrogen peroxide
$(H_2O_2)$ . Proc. Soc. Exp. Biol.Med. 158, 478-481. https://doi.org/10.3181/00379727-158-40230 - Ishiyama, S., Hiroe, M., Nishikawa, T., Abe, S., Shimojo, T., Ito,H., Ozasa, S., Yamakawa, K., Matsuzaki, M., Mohammed, M.,Nakazawa, H., Kasajima, T. and Marumo, F. (1997) Nitricoxide contributes to the progression of myocardial damages inexperimental autoimmune myocarditis in rats. Circulation 95,489-496. https://doi.org/10.1161/01.CIR.95.2.489
- Kaul, N., Siveski-Iiiskovic, N., Slezak, J. and Singal, P. K. (1993)Free radicals and the heart. J. Pharmacol. Toxicol. Meth. 30,55-67. https://doi.org/10.1016/1056-8719(93)90008-3
- Misko, T. P., Moore, W. M., Kasten, T. P., Nickols, G. A., Corbett,J. A., Tilton, R. G., McDaniel, M. L. Williamson, J. R. andCurrie, M. (1993) Selective inhibition of the inducible nitric oxide synthase by aminoguanidine. Eur. J. Pharmacol. 233,119-125. https://doi.org/10.1016/0014-2999(93)90357-N
- Morishima, I., Matsui, H., Mukawa, H., Hayashi, K., Toki, Y.,Okumura, K., Ito, T. and Hayakawa, T. (2000) Melatonin apineal hormone with antioxidant property protect againstadriamycin cardiomyopathy in rats. Life Science 63, 511-521.
- Mostafa, A. M., Nagi, M. N., Al Rikabi, A. C., Al-Shabanah, O.A. and El-Kashef, H. A. (1999) Protective effect ofaminoguanidine against cardiovascular toxicity of chronicdoxorubicin treatment in rats. Res. Commun. Mol. Pathol.Pharmacol. 106, 193-202.
- Myers, C. (1998) The role of iron in doxorubicin-inducedcardiomyopathy. Semin. Oncol. 25, 10-14.
- Myers, C. E., McGuire, W. P., Liss, R. H., Ifirm, I., Grotzinger, K.and Young, R. C. (1997) Adriamycin: The role of lipidperoxidation in cardiac toxicity and tumor response. Science19, 165-167.
- Nagi, M. N. and Mansour, M. A. (2000) Protective effect ofthymoquinone against doxorubicin-induced cardiotoxicity inrats: a possible mechanism of protection. Pharmacol. Res. 41,283-289. https://doi.org/10.1006/phrs.1999.0585
- Nathan, C. (1992) Nitric oxide as a secretory product ofmammalian cells. FASEB. J. 6, 3051-3064.
- Ohkawa, H., Ohishi, N. and Yagi, K. (1979) Assay of lipidperoxides in normal tissues by thiobarbituric acid reaction.Anal. Biochem. 95, 351-358. https://doi.org/10.1016/0003-2697(79)90738-3
- Pryor, W. A. and Squadrito, G. L. (1995) The chemistry ofperoxynitrite a product from reaction of nitric oxide withsuperoxide. Am. J. Physiol. 12, 699-722.
- Seif-el-Nasr, M. and Fahim, A. T. (2001) Antioxidant effect of N-omega-nitro-L-arginine methyl ester (L-NAME) on global cerebral ischemia in a rat model. Arzneimittelforschung 51, 628-632.
- Singal, P. K., Deally, C. M. R. and Weinberg, L. E. (1987)Subcellular effects of adriamycin in the heart: a concise review.J. Mol. Cell Cardiol. 19, 817-828 https://doi.org/10.1016/S0022-2828(87)80392-9
- Singal, P. K. and Pierce, G. N. (1986) Adriamycin stimulates lowaffinity calcium binding and lipid peroxidation but depressesmyocardial function. Am. J. Physiol. 1250, 419-425.
- Singal, P. K., Siveski-Iliskovic, N., Hill, M., Thomas, T. and Li, T.(1995) Combination therapy with probucol preventsadriamycin-induced cardiomyopathy. J. Mol. Cell Cardiol. 27,1055-1063. https://doi.org/10.1016/0022-2828(95)90074-8
- Siveski-Iliskovic, N., Kaul, N. and Singal, P. K. (1994) Probucolpromotes endogenous antioxidants and provides protectionagainst adriamycin-induced cardiomyopathy in rats. Circulation89, 2829-2835. https://doi.org/10.1161/01.CIR.89.6.2829
- Tong, J., Ganguly, P. K. and Singal, P. K. (1991) Myocardialadrenergic changes in two stages of heart failure due toadriamycin treatment in rats. Am. J. Physiol. 620, 909-916.
- Vivar, V. J., Martasek, P., Hogg, N., Masters, B. S. S., Pritchard,K. A. and Kalyanaraman, B. (1997) Endothelial nitric oxidesynthase dependent superoxide generation from adriamycin.Biochemistry 36, 11293-11297. https://doi.org/10.1021/bi971475e
- Xu, M. F., Tang, P. L., Qian, Z. M. and Ashraf, M. (2001) Effectsby doxorubicin on the myocardium are mediated by oxygenfree radicals. Life Sci. 12, 889-890.
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