Journal of Gastric Cancer
- Volume 3 Issue 4
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- Pages.214-220
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- 2003
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- 2093-582X(pISSN)
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- 2093-5641(eISSN)
Loss of Heterozygosity and Microsatellite Instability at Multiple Tumor Suppressor Genes in Gastric Carcinomas
위암에서 여러 종양억제유전자 부위의 이형접합성 소실과 현미 부수체 불안정성
- Cho Young Gu (Departments of Pathology College of Medicine, The Catholic University of Korea) ;
- Kim Chang Jae (Departments of Pathology College of Medicine, The Catholic University of Korea) ;
- Park Cho Hyun (Departments of Surgery, College of Medicine, The Catholic University of Korea) ;
- Kim Young Sil (Departments of Pathology College of Medicine, The Catholic University of Korea) ;
- Kim Su Young (Departments of Pathology College of Medicine, The Catholic University of Korea) ;
- Nam Suk Woo (Departments of Pathology College of Medicine, The Catholic University of Korea) ;
- Lee Sug Hyung (Departments of Pathology College of Medicine, The Catholic University of Korea) ;
- Yoo Nam Jin (Departments of Pathology College of Medicine, The Catholic University of Korea) ;
- Lee Jung Young (Departments of Pathology College of Medicine, The Catholic University of Korea) ;
- Park Won Sang (Departments of Pathology College of Medicine, The Catholic University of Korea)
- 조용구 (가톨릭대학교 의과대학 병리학교실) ;
- 김창재 (가톨릭대학교 의과대학 병리학교실) ;
- 박조현 (가톨릭대학교 의과대학 외과학교실) ;
- 김영실 (가톨릭대학교 의과대학 병리학교실) ;
- 김수영 (가톨릭대학교 의과대학 병리학교실) ;
- 남석우 (가톨릭대학교 의과대학 병리학교실) ;
- 이석형 (가톨릭대학교 의과대학 병리학교실) ;
- 유남진 (가톨릭대학교 의과대학 병리학교실) ;
- 이정용 (가톨릭대학교 의과대학 병리학교실) ;
- 박원상 (가톨릭대학교 의과대학 병리학교실)
- Published : 2003.12.01
Abstract
Purpose: The aim of this study was to investigate the frequency of loss of heterozygosity and the microsatellite instability at multiple tumor suppressor gene loci in gastric adenocarcinomas. Materials and Methods: Loss of heterozygosity and the microsatellite instability at several tumor suppressor gene loci were analyzed in 29 primary gastric carcinomas by using microdissection and the polymerase chain reaction. Results: Twenty-three (