A study on the release of nickel and chromium from simulated orthodontic appliances

교정장치로부터의 니켈과 크롬의 유리에 관한 연구

  • Ryu, Jeong-Hyun (Department of Orthodontcis, School of Dentistry, Wonkwang University) ;
  • Oh, Soh-Taek (Department of Orthodontcis, School of Dentistry, Wonkwang University) ;
  • Kang, Kyung-Wha (Department of Orthodontcis, School of Dentistry, Wonkwang University) ;
  • Kim, Sang-Cheol (Department of Orthodontcis, School of Dentistry, Wonkwang University)
  • 류정현 (원광대학교 치과대학 교정학교실) ;
  • 오소택 (원광대학교 치과대학 교정학교실) ;
  • 강경화 (원광대학교 치과대학 교정학교실) ;
  • 김상철 (원광대학교 치과대학 교정학교실)
  • Published : 2003.10.01

Abstract

Nickel and chromium are two major metals used in the alloys of most orthodontic appliances. But these metals are known to cause hypersensitivity, dermatitis, and asthma. In addition, a significant carcinogenic and mutagenic potential has been demonstrated for compounds containing these metals. The purpose of this study was to find out how much nickel and chromium was released from orthodontic appliances, and which factors would influence the release. The simulated orthodontic appliances were constructed for a half of a mandibular arch and incubated in $0.05\%$ NaCl solution at $37^{\circ}C$. Nickel and chromium release was quantified with an Inductively Coupled Plasma (ICP) spectroanalyzer. The results were as follows : 1. From simulated orthodontic appliances, nickel was released $9.83-70.0{\mu}g/day$ but the release of chromium was not detectable in Limit of 10ppb. 2. The amount of nickel release was significantly different between the types of appliances. 3. The galvanic condition increased the amount of nickel release, which was not statistically significant. 4. The sand blasting increased the amount of nickel release, which was also not statistically significant.

니켈과 크롬은 대부분의 교정장치를 제작하는데 사용되는 합금을 구성하는 주요한 금속이다. 그러나 이들 금속은 과민반응, 피부염, 천식 등의 주요한 원인이 되며, 이들 금속의 우발적인 흡입에 의해 암이 유발될 수 있음이 보고된 바 있다 이에 하악 standard edgewise브라켓을 이용한 사분악의 교정장치를 $37^{\circ}C,\;,0.05\%$ NaCl용액에 저장하여 교정장치의 부식에 의해 유리된 니켈과 크롬을 Inductively Coupled Plasma(ICP) spectroanalyzer를 이용하여 측정하였다. 교정장치로부터, 1일 평균 $9.83-70.0{\mu}g/day$의 니켈이 유리되었으나, 크롬은 10ppb 측정한계에서 측정불가능 하였다. 니켈 유리량은 제품에 따라 유의한 차이를 가져왔다 Galvanic조건이나 Sand blasting처리는 니켈 유리량에 증가를 가져왔으나 통계학적으로 유의하지 않았다.

Keywords

References

  1. Psaila-Savona P. Health hazards associated with base metal alloys. Aust Soc Prosthodontists Bull 1982 : 12 : 4-7
  2. Bencko V. Nickel : a review of its occupational and environmental toxicology. J Hyg Epidemiol Microbiol Immunol 1983: 27 : 237-7
  3. National Institute of Dental Research. Workshop: biocompatibility of metals in dentistry. J Amer Dent Assoc 1984 : 109 : 469-71
  4. Moffa JP. Biocompatibility of nickel based dental alloys. Calif Dent Assoc J 1984 : 12 : 45-51
  5. Council on Dental Materials, Instruments, and Equipment : Biological effects of Nickel-containing dental alloys. J Am Dent Assoc 1982 : 104: 501-5
  6. Eggleston DW. Effect of dental amalgam and nickel alloys on Tlymphocytes: Preliminary report. J Prosthet Dent 1984 : 51 : 617-23
  7. Schriver WR, Shereff RH, Domnitz JM, Swintak EF, Civjan S. Allergic response to stainless steel wire. Oral Surg Oral Med Oral Pathal 1976 : 42 : 578-81
  8. Fisher AA. Contact Dermatitis, ed. 2. 1973, Lea & Febiger, Publishers
  9. Rickles NE, Fine H, Cisneros GJ, Allergy in surface lesions of the oral mucosa. Oral Surg Oral Med Oral Pathal 1972 : 33 : 744-54
  10. Bass JK. Nickel hypersensitivyty in the Orthodontic patient Am J Orthod Dentofac Orthop 1993 : 103 : 280-5
  11. Rickles NH. Oral Pathology, New York, 1965, McGraw-Hill Book Company, Inc., pp, 501-34
  12. Temesvari E, Racz I. Nickel sensitivity from dental Prosthesis. Contact Dermatitis 1988 : 18 : 50-1
  13. Espana A, Alonso M, Soria C, Guimaraens D, Ledo A Chronic urticaria after implantation of two nickel-containing dental prosthesis in a nickel-allergic patient Contact Dermatitis 1989: 21 : 204-5
  14. Jones TK, Hansen CA, Singer MT, Kessler HP. Dental implications of nickel hypersentitivity. J Prosthet Dent 1986 : 56 : 507-9
  15. Blanco-Dalman L, Carrasquillo-Alberty E, Silva-Parra J. A study of nickel allergy. J Prosthet Dent 1984 : 52 : 116-9
  16. Janson GRP, Dainesi EA, Consolaro A, Woodside DG, de Freitas MR. Nickel hypersensitivity reaction before, during, and after orthodntic therapy. Am J Orthod Dentofac Orthop 1998 : 113 : 655-60
  17. Bishara SE, Barrett RD, Selim MI. Biodegradation of orthodontic appliances. Part II. Changes in the blood level of nickel. Am J Orthod Dentofac Orthp 1993 : 103 : 115-9
  18. Park HY, Shearer TR. In vitro release of nickel and chromium from simulated orthodontic appliances. Am J Orthod Dentofac Orthop 1983 : 84: 156-9
  19. Grimsdottir MR, Gjerdet NR, Hensten-Pettersen A. Composition and in vitro corrosion of orthodontic appliances, Am J Orthod Dentofac Orthop 1992 : 101 : 525-32
  20. Barrett RD, Bishara SE, Quinn JK. Biodegradation of orthodontic appliances. Part I. Biodegradation of nickel and chromium in vitro. Am J Orthod Dentofac Orthop 1993 : 103 : 8-14
  21. Schroeder HA, Balassa JJ. Tipton IH. Abnormal trace metals in man-nickel J chron Dis 1961 : 15 : 51-65
  22. Maijer R, Smith DC. Corrosion of orthodontic bracket bases. Am J Orthod Dentofac Orthop 1982 : 81 : 43-8
  23. Block GU, Yeung M. Asthma induced by nickel. J Amer Med Assoc 1982 : 247 : 1600-2 https://doi.org/10.1001/jama.247.11.1600
  24. Fisher JR, Rosenblum GA, Thomson BD. Asthma induced by nickel. J Amer Med Assoc 1982 : 248 : 1065-6
  25. Maijer R, Smith DC. Biodegradation of the orthodontic bracket system. Am J Orthod Dentofac Orthop 1986 : 90 : 195-8
  26. Gell PGH, Coombs RRA. Clinical Aspects of Immunology, ed. 2. Philadelphia, 1969, F.A.Davis Company
  27. Ceen RF, Gwinnett AJ. Indelible Iatrogenic staining of enamel following debonding A case report. J Clin Orthod 1980 : 14 : 713-5
  28. Buchman DJL. Effects of recycling on metallic direct-bond orthodontic brackets. Am J Orthod Dentofac Orthop 1980 : 77 : 654-68