Korean Journal of Acupuncture

Society for Meridian and Acupoint (경락경혈학회)
권호 표지

The Scavenging Effect on NO, DPPH and Inhibitory Effect on IL-4 in Schizandrae Fructus Herbal-Acupuncture Solution

오미자약침액(五味子藥鍼液)의 NO, DPPH 소거(消去) 및 IL-4에 대한 억제효과(抑制效果)

  • Cho Hyun-Yeul (Dept. of Acupuncture & Moxibustion, College of Oriental Medicine, Kyung-san University) ;
  • Yoon Jong-Seok (Dept. of Acupuncture & Moxibustion, College of Oriental Medicine, Kyung-san University) ;
  • Seo Bo-Myung (Dept. of Acupuncture & Moxibustion, College of Oriental Medicine, Kyung-san University) ;
  • Lee Sea-Youn (Dept. of Acupuncture & Moxibustion, College of Oriental Medicine, Kyung-san University) ;
  • Kim Sung-Woong (Dept. of Acupuncture & Moxibustion, College of Oriental Medicine, Kyung-san University) ;
  • Baek Jung-Han (Je-Han Oriental Medical Academy) ;
  • Park Chi-Sang (Je-Han Oriental Medical Academy) ;
  • Seo Jeong-Chul (Dept. of Acupuncture & Moxibustion, College of Oriental Medicine, Kyung-san University) ;
  • Han Sang-Won (Dept. of Acupuncture & Moxibustion, College of Oriental Medicine, Kyung-san University)
  • 조현열 (경산대학교 한의과대학 침구학교실) ;
  • 윤종석 (경산대학교 한의과대학 침구학교실) ;
  • 서보명 (경산대학교 한의과대학 침구학교실) ;
  • 이세연 (경산대학교 한의과대학 침구학교실) ;
  • 김성웅 (경산대학교 한의과대학 침구학교실) ;
  • 백정한 (제한동의학술원) ;
  • 박치상 (제한동의학술원) ;
  • 서정철 (경산대학교 한의과대학 침구학교실) ;
  • 한상원 (경산대학교 한의과대학 침구학교실)
  • Published : 2003.03.27
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Abstract

Backgrounds : It has been investigated about ageing theory. However, ageing mechanism still remains to be unknown. Since Harman proposes that ageing and ageing related diseases might be due to oxidative damage and these are modifiable by genetic and environmental factors. For designing an optimal nutritional countermeasure against ageing and ageing related disease, it is necessary to understand the ageing mechanism and other reactive species. Objectives : Schizandra Chinesis has been clinically used to treat brain disease, respiratory or inflammatory disease etc. in Oriental medicine. The purpose of this study is to investigate the scavenging effect of Schizandrae Fructus herbal-acupuncture solution(SFHA) on NO, DPPH and IL-4. Results : The results are summarized as follows; (1) There is a significant scavenging effect of SFHA on NO in 0.1, 1, 10mg/ml group after 24hrs. (2) There is a significant scavenging effect of SFHA on DPPH in 1, $10{\mu}g/ml$ group. (3) There is a significant inhibitory effect of SFHA on IL-4 in 1, 10, $100{\mu}g/ml$ group. Conclusions : These findings indicate that SFHA can be used as antioxidant or antiimflammatory drug. But further study is needed about the effect of SFHA.

Keywords

References

  1. 東醫老年養生學(1판) 김광호;김동영
  2. Experimental Gerontology v.36 Oxidative biochemical markers:clues to understanding aging in long-lived species Floyd RA;West M;Hensley K
  3. 大韓鍼灸學會誌 v.18 no.1 老化의 硏究動向에 관한 考察 이홍민;서정철;김용석
  4. Crit Rev Toxicol. v.23 Free radicals as mediators of tissue injury and disease Kehrer JP
  5. 大韓鍼灸學會誌 v.13 no.2 當歸藥鍼液의 抗酸化 效能에 관한 硏究 安埈撤;文振榮;林鍾國
  6. 本草學(2판) 全國韓醫科大學 本草學敎室
  7. 中藥大辭典 江蘇醫學院
  8. 和漢藥 赤松金芳
  9. 中藥藥理與應用 旺容生(外)
  10. J Assoc Off Anal Chem. v.65 no.3 Interaction between sample preparation techniques and three methods of nitrite determination Fox JB;Doerr RC;Lakritz L
  11. Yakugaku Zasshi v.88 no.6 Biochemical studies of the physiological function of tocopheronolactone Uchiyama M;Suzuki Y;Fukuzawa K
  12. Biochem Pharmacol. v.37 no.6 Interaction of flavonoids with 1,1-diphenyl-2-picrylhydrazyl free radical, liposomal membranes and soybean lipoxygenase-1 Ratty AK;Sunamoto J;Das NP
  13. Med Lab Sci. v.49 no.4 Aging and free radicals Gutteridge JM
  14. 프리라디칼(1판) 김영균;김영곤
  15. Bull. Yosu Nat'l Univ. v.14 Development of Anti-Oxidatant Tea for Anti-aging Kim JD(et al)
  16. J of Korean Oil Chemists' Soc. v.14 Separation of Antioxidant compounds from Persimmon leaves Shin DH
  17. 간추린 병리학(2판) 대한병리학회 대구경북지부학회
  18. 대한내과학회지 v.36 no.2 폐동맥내피세포에서의 cytokinine 및 내독소에 의한 nitris oxide형성과 미토큰드리아 aconitase 활성도의 관계 장상호;장준;박전한;김세규;김세종;김서규 等
  19. 대한안과학회지 v.40 no.11 유색가토의 유리체강내에 Nitric Oxide를 주사시 망막에 미치는 영향에 대한 연구 박영진;임충식, 권년수, 양한남
  20. Korean Journal of Ophthalmology v.15 no.2 The role of nitric oxide in ocular surface diseases Jae Chan Kim
  21. 동의생리병리학회지 v.15 no.6 Scavenging Effect of Several Distilled Herbal Acupunctures on Nitric Oxide 한상원;임강현;서정철;윤현민;장경전;송춘호(외)
  22. 大韓鍼灸學會誌 v.18 no.6 Scavenging Effect of Bee Venom for Acua-acupuncture against Nitric Oxide 서정철;임강현;김이화;김창주;유영민;정주호(외)
  23. 大韓鍼灸學會誌 v.15 no.2 柴胡藥鍼製劑의 自由基 消去能 및 脂質過酸化 抑制效能에 관한 硏究 林鍾國;文振榮
  24. 大韓本草學會誌 v.15 no.2 薏苡仁과 苦蔘의 抗酸化作用에 관한 硏究 朴涌基;康秉秀
  25. 高麗人蔘學會誌 v.23 no.3 홍삼으로부터 분리한 수용성 갈변물질의 항산화 활성. DPPH의 수소공여능 및 hydrogen peroxide 소거능 중심으로 이종원
  26. 釜山水産大生命科學硏究報告 v.5 no.1 Alaternin, Cassiaside and Rubrofusarin gentiobioside, Radical Scavenging Principles from the Seeds of Cassia tora on 1,1-Diphenyl -2-picrylhy-drazyl(DPPH) Radical Choi Jae Sue(外)
  27. 免疫學(1판) 김세종
  28. Korean J Immunol. v.19 Cytokine이 Th1細胞의 Mitogens에 대한 增殖反應에 미치는 影響 정승원;이미애;하대유
  29. 臨床呼吸器學 韓鏞徹
  30. 定喘湯과 淸上補下湯이 asthma model 內의 cytokine에 미치는 影響 金永佑
  31. 中華臨床中藥學(4판) 雷載權;張廷模(主編)
  32. 中藥藥效與臨床 丁兆夢(編著)
  33. 대한내과학회지 v.40 no.2 만성활동성 간질환 환자에서 diphenyl-dimethyl-dicarboxylate의 혈청 Alanine Aminotransferase치 저하효과에 관한 전향적 무작위 선정 대조연구 송인성;김용태;정현채;이효석;김정용;윤용범
  34. 사상의학회지 v.13 no.3 소음인 숭양익기탕의 면역조절작용 유창렬;송정모
  35. 慶熙醫學 v.54 麥門冬과 五味子가 Asthma model 內의 Cytokine IL-4, IL-5, IL-6에 미치는 影響 이동생;정희재;이형구;정승기
  36. 大韓韓方內科學會誌 v.21 no.1 杏仁과 桔模이 Asthma model 내의 Cytokine IL-4,IL-5, IL-6에 미치는 영향 정욱;정희재;정승기;이형구
  37. 大韓經絡經穴學會誌 v.18 no.2 腎兪穴의 鍼灸戟과 黃耆藥鍼이 실험용 생쥐의 면역활성 Cytokine인 IL-4의 유전자발현에 미치는 영향 김법진;박수영;김창환;김철호;문진영;최달영;김준기;박선동;박원환