Advances in Traditional Medicine

Kyung Hee Oriental Medicine Research Center (경희대학교 융합한의과학연구소)
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Reductive effect of body weight in rats fed a high-fat diet by Sense-line

  • An, Hyo-Jin (College of Pharmacy and KI Co., Ltd., Wonkwang University) ;
  • Chung, Hwan-Suck (College of Pharmacy and KI Co., Ltd., Wonkwang University) ;
  • Jeong, Hyun-Ja (College of Pharmacy and KI Co., Ltd., Wonkwang University) ;
  • Lee, Soon-Ah (College of Pharmacy and KI Co., Ltd., Wonkwang University) ;
  • Kim, Hyung-Min (College of Pharmacy and KI Co., Ltd., Wonkwang University) ;
  • Baek, Seung-Hwa (Department of Natural Products, Professional Graduate School of Oriental Medicine, Wonkwang University)
  • Published : 2003.02.28
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Abstract

Sense-line (SL), a dietary functional food, is our invention for weight loss. To evaluate such an effect of SL, we analyzed the plasma levels of total cholesterol, low-density lipoprotein (LDL) cholesterol, high-density lipoprotein (HDL) cholesterol, and weight changes after rats were fed on high fat diet with SL for 20 days. Plasma total cholesterol level and LDL-cholesterol level was decreased by 52% and 91.89% in 5% SL treated group and by 13% and 51.45% in 10% SL treated group, respectively. But HDL-cholesterol was not changed. In addition, the weight was significantly lower in SL group than in high-fat diet group (P<0.05). Our findings indicate that SL may contain compounds with actions, which can treat blood circulatory trouble as well as overweight.

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