Korean Journal of Oriental Medicine (한국한의학연구원논문집)
- Volume 9 Issue 2
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- Pages.55-67
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- 2003
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- 1229-3377(pISSN)
Inhibition of Whole Blood Platelet aggregation from Traditional medicines
한약재의 전혈혈소판응집억제
- Jeon, Won-Kyung (Korea Institute of Oriental Medicine) ;
- Kim, Jung-Hee (Korea Institute of Oriental Medicine) ;
- Lee, A-Yeong (Korea Institute of Oriental Medicine) ;
- Kim, Ho-Kyoung (Korea Institute of Oriental Medicine)
- Published : 2003.12.30
Abstract
To evaluate anti-aggregatory activity of traditional prescriptions and medicines for treatment of Ohyul symptom, 70% methanol extracts were examined using collagen stimulated in vitro platelet aggregation by impedance method in rat whole blood. The crude extracts from DoHaekSeungKiTang, BoYangHwanOhTang, Caesalpinia sappan, Rhus verniciflua, Rheum palmatum, Polygonum cuspidatum, Salvia miltiorrhiza were found to inhibit platelet aggregation. The effective crude extracts of traditional medicine were fractionated to dichloromethane, ethyl acetate, butanol and aqueous layer. Polygonum cuspidatum, Caesalpinia sappan aud Rhus verniciflua ethyl acetate fractions concentration-dependently
Keywords
- anti-aggregatory activity;
- collagen;
- Dohackseongkitang;
- Polygonum cuspidatum;
- Caesalpinia sappan;
- Rhus vernicflua