Korean Journal of Pharmacognosy (생약학회지)

The Korean Society of Pharmacognosy (한국생약학회)
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Effects of Rhus verniciflua Stokes (RVS) Extract on Diet-induced Obesity in C57BL/6 mouse

옻나무 추출물이 식이에 의한 비만유도 C57BL/6 mouse에 미치는 영향

  • Kim, Jung-Hee (Quality Control of Herbal Medicine Department, Korea Institute of Oriental Medicine) ;
  • Lee, Hye-Won (Quality Control of Herbal Medicine Department, Korea Institute of Oriental Medicine) ;
  • Ko, Byoung-Seop (Quality Control of Herbal Medicine Department, Korea Institute of Oriental Medicine) ;
  • Kim, Ho-Kyoung (Quality Control of Herbal Medicine Department, Korea Institute of Oriental Medicine) ;
  • Jeon, Won-Kyung (Quality Control of Herbal Medicine Department, Korea Institute of Oriental Medicine)
  • 김정희 (한국한의학연구원 검사사업부) ;
  • 이혜원 (한국한의학연구원 검사사업부) ;
  • 고병섭 (한국한의학연구원 검사사업부) ;
  • 김호경 (한국한의학연구원 검사사업부) ;
  • 전원경 (한국한의학연구원 검사사업부)
  • Published : 2003.12.30
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Abstract

We investigated the effects of Rhus verniciflua Stokes (RVS) on high fat diet- induced obesity in C57BL/6 that received ad libitum exposure to a high fat diet for 8 weeks. Male C57BL/6 mice weighing $20.1{\pm}0.95\;g$ were divided into four groups and the body weight and food intake were weighed for 8 weeks. After the administration of RVS extract, the liver, subcutaneous and retroperitoneal adipose tissue in the mice were weighed and common blood count in whole blood and biochemical parameters in plasma were measured. It was founded that body weight increase was significantly suppressed by the oral administration of RVS extract in group with high fat diet. Weight of subcutaneous adipose tissue and concentration of triglyceride in plasma from mice which were administrated RVS extract were lower than obesity control group. These results suggest that RVS extract may effect on inhibition of diet-induced obesity.

Keywords

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