Korean Journal of Pharmacognosy (생약학회지)

The Korean Society of Pharmacognosy (한국생약학회)
권호 표지

Flavonoid Constituents and Their Antioxidant Activity of Laportea bulbifera Weddell

혹쐐기풀의 Flavonoid 성분 및 항산화 효과

  • Yang, Min-Cheol (Natural Products Laboratory, College of Pharmacy, SungKyunKwan University) ;
  • Choi, Sang-Zin (Natural Products Laboratory, College of Pharmacy, SungKyunKwan University) ;
  • Lee, Sung-Ok (Natural Products Laboratory, College of Pharmacy, SungKyunKwan University) ;
  • Chung, Ae-Kyung (Natural Products Laboratory, College of Pharmacy, SungKyunKwan University) ;
  • Nam, Jung-Hwan (Natural Products Laboratory, College of Pharmacy, SungKyunKwan University) ;
  • Lee, Kyu-Ha (Natural Products Laboratory, College of Pharmacy, SungKyunKwan University) ;
  • Lee, Kang-Ro (Natural Products Laboratory, College of Pharmacy, SungKyunKwan University)
  • 양민철 (성균관대학교 약학대학 천연물약품화학연구실) ;
  • 최상진 (성균관대학교 약학대학 천연물약품화학연구실) ;
  • 이성옥 (성균관대학교 약학대학 천연물약품화학연구실) ;
  • 정애경 (성균관대학교 약학대학 천연물약품화학연구실) ;
  • 남정환 (성균관대학교 약학대학 천연물약품화학연구실) ;
  • 이규하 (성균관대학교 약학대학 천연물약품화학연구실) ;
  • 이강노 (성균관대학교 약학대학 천연물약품화학연구실)
  • Published : 2003.03.30
Download PDF
⟨ Previous Next ⟩

Abstract

The repeated column chromatographic separation of the MeOH extract of Laportea bulbifera Weddell resulted in the isolation of five flavonoids. Structures of the isolated compounds have been identified as $isorhamnetin-7-O-{\alpha}-L-rhamnoside$ (1), $isorhamnetin-3-O-{\alpha}-L-rhamnoside$ (2), $isorhamnetin-3,7-O-{\alpha}-L-dirhamnoside$ (3), $isorhamnetin-3-O-{\alpha}-L-rhamnopyranosyl-(1{\rightarrow}2)-{\beta}-galactopyranoside$ (4), $isorhamnetin-3-O-{\alpha}-rhamosyl-(1{\rightarrow}2)-rhamnoside$ (5) by spectroscopic means.

Keywords

References

  1. 이창복(1985) 대한식물도감, 290. 향문사, 서울
  2. 이우철(1996) 원색한국기준식물도감, 69. 도서출판 아카데미, 서울
  3. 강창민, 신민교, 이경순, 안덕균(1999) 중약 대사전, 2782-2783. 도서출판정담, 서울
  4. 안덕균(1998) 원색 한국본초도감, 339. 교학사, 서울
  5. 송주택(1989) 식물 대보감(상). 190. 도서출판 일흥, 서울
  6. 윤국병, 장준근(1989) 몸에 좋은 산야초, 153. 석오 출판사, 서울
  7. Leung, T. W., Williams, D. H., Barna, J. C., Forti, S. and Oelrichs, P. B. (1986) Structural studies on the peptide moroidin from Laportea moroide. Tetrahedron. 43(12): 3333-3348
  8. Hiroshi, M., Kazutaka, S., Hideyuki, S. and Junichi, K. (2000) Antimitotic activity of moroidin, a bicyclic peptide from the seeds of Celosia argentrea. Bioorg. & Med. Chern. Lett. 10: 469-471 https://doi.org/10.1016/S0960-894X(00)00029-9
  9. Jun'ichi, K., Hayato, S., Kazutaka, S., Koichi, T. and Hiroshi, M. (2001) Celogentin A-C, New antimitotic bicyclic peptide from the seeds of Celosia argentea. J. Org. Chern. 66: 66266633 https://doi.org/10.1021/jo0103423
  10. 유승조, 곽종환(1989) 국내 자생 식물의 화학 성분 검색. Kor. J. Pharmacogn. 20(3): 149-153
  11. Choi, J. S., Jung, M. J., Park, H. J., Chung, H. Y, and Kang, S. S. (2002) Further isolation of peroxynitrite and 1,1diphenyl-2-picrylhydrazyl scavenging isorhamnetin 7-O-glucoside from the leaves of Brassicajuncea L. Arch. Pharm. Res. 25(5): 645-627
  12. 강삼식, 최재수, 우원식, 지형준(1983) Isorhamnetin 7-O-glucoside from the leaves of Typha latifolia. Kor. J. Pharmacogn. 14(4): 137-139
  13. Markham, K. R. (1982) Techniques of flavonoid identification. 52-53. Academic press
  14. 정칠만, 황은주, 권학철, 김선여, 배기환, 지옥표, 이강노(1999) 고추나물의 항산화 활성 flavonoid 성분. Kor. J. Pharmacogn. 30(2): 196-201
  15. Chung, I. M., Kim, K. H., K., Ahn, J. K., and Lee, J. O. (2000) Varietal variation in antioxidant activity of rice grain by DPPH and TBA Methods. Korean J. Crop Sci. 45(4): 261266
  16. Yoshida, T., Mori, K., Hatano, T., Okumura, T., Uehara, I., Komagoe, K., Fujita, Y and Okuda, T. (1989) Studies on inhibition mechanism of autoxidation by tannins and flavonoids. V. Radical-scavenging effects of tannins and related polyphenols on l,l-diphenyl-2-picrylhydrazyl radical. Chern. Pharm. Bull. 37(7): 1919-1921 https://doi.org/10.1248/cpb.37.1919
  17. Dey, P. M. and Harbone, J. B. (1989) Method in plant biochemistry, vol 1, 209-216. Academic press
  18. Maria, W. (1989) Flavonol glycosides from Sedum album. Phytochemistry. 28(8): 2187-2189 https://doi.org/10.1016/S0031-9422(00)97941-X
  19. Maria, W. and Maria, K. (1989) Flavonol glycosides from Sedum acre. Phytochemistry. 27(12): 3941-3943 https://doi.org/10.1016/0031-9422(88)83050-4
  20. Singh, K. N. and Pandey, V. B. (1986) Isorhamnetin 7-glucoside from Cnicus wallichi. Phytochemistry. 25(11): 2683 https://doi.org/10.1016/S0031-9422(00)84544-6
  21. Liu, K. C., Yang, S. L., Roverts, M., and Phillipson, J. D. (1989) Eupafolin rhamnosides from Kalanchoe gracilis. .J. Nat. Prod. 52(5): 970-974 https://doi.org/10.1021/np50065a009
  22. Agrawal, P. K. (1989) Carbon-13 NMR of flavonoids, 284-312. Elsevier. Amsterdam
  23. Komissarenko, N. F. (1988) Flavonoids of Inflorescences of Calendula officinalis. Khim. Prir. Soedin.: 675-680
  24. Williams, C. A., Harbone, J. B., and Eagles, J. (1989) Leaf flavonoid diversity in the Australian genus Patersonia. Phytochemistry. 28(7): 1891-1896 https://doi.org/10.1016/S0031-9422(00)97881-6
  25. Reynaud, J., Vinzani, F. (1988) The flavonoids of Senecio incanus. Pharmazie. 43(12): 878-879
  26. Mohamed, S., Mohamed, E. A. and Nabiel, S. (1997) Flavonoids of four Cleome and three Capparis species. Biochem. System. Ecol. 25(2): 161-166 https://doi.org/10.1016/S0305-1978(96)00099-3
  27. Mizuno, M., Kyotani, Y., Ilnuma, M., Tanaka, T., Kojima, H., Iwatsuki K. (1991) Mearnsetin 3,7 dirhamnoside from Asplenium antiquum. Phytochemistry. 30(8): 2817-1818 https://doi.org/10.1016/0031-9422(91)85158-V
  28. Ahmed, A., Fikria, A. (1987) Flavonoid from Cleome droserifolia. Egypt. J. Pharm. Sci. 28: 313-318
  29. Kaouadji, M. (1990) Flavonol diglycosides from Blackstonia perfoliata. Phytochmistry. 29(4): 1345-1347 https://doi.org/10.1016/0031-9422(90)85465-R