Tuberculosis and Respiratory Diseases

The Korean Academy of Tuberculosis and Respiratory Diseases (대한결핵및호흡기학회)
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A Case of Microscopic Polyangiitis Presenting As Diffuse Alveolar Hemorrhage

미만성 폐포출혈 양상을 나타낸 현미경적 다발성 혈관염 1례

  • Seo, Chang-Gyun (Department of Internal Medicine Keimyung University School of Medicine) ;
  • Lee, Seung-Hyun (Department of Internal Medicine Keimyung University School of Medicine) ;
  • Kim, Sang-Hyun (Department of Internal Medicine Keimyung University School of Medicine) ;
  • Kim, Kyung-Chan (Department of Internal Medicine Keimyung University School of Medicine) ;
  • Kim, Min-Su (Department of Internal Medicine Keimyung University School of Medicine) ;
  • Han, Seung-Beom (Department of Internal Medicine Keimyung University School of Medicine) ;
  • Park, Kwan-Kyu (Department of Pathology Keimyung University School of Medicine) ;
  • Jeon, Young-June (Department of Internal Medicine Keimyung University School of Medicine)
  • 서창균 (계명대학교 의과대학 내과학교실) ;
  • 이승현 (계명대학교 의과대학 내과학교실) ;
  • 김상현 (계명대학교 의과대학 내과학교실) ;
  • 김민수 (계명대학교 의과대학 내과학교실) ;
  • 김경찬 (계명대학교 의과대학 내과학교실) ;
  • 한승범 (계명대학교 의과대학 내과학교실) ;
  • 박관규 (계명대학교 의과대학 병리학교실) ;
  • 전영준 (계명대학교 의과대학 내과학교실)
  • Published : 2002.08.30
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Abstract

A diffuse alveolar hemorrhage is a rare manifestation in microscopic polyangiitis. Recently we experienced a case of diffuse alveolar hemorrhage associated with microscopic polyangiitis, which was diagnosed with the typical clinical manifestations, ANCA and a renal biopsy. A 71 year old female was admitted complaining of coughing and dyspnea. A chest X-ray, HRCT and BAL revealed a diffuse alveolar hemorrhage. A diffuse alveolar hemorrhage was noted during a bronchoscopy. She also had proteinuria, microscopic hematuria and mild azotemia. The renal biopsy showed necrotic glomerulonephritis without immune complex deposits or granuloma. Under the diagnosis of microscopic polyangiitis, she was treated with steroid pulse therapy, and prednisolone with cyclophosphamide subsequently. She showed marked improvement in the clinical manifestations.

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