Numb chin 증후군으로 발현한 전이성 비소세포 폐암 1예

A Case of Metastatic Non-small Cell Lung Cancer Presenting with Numb Chin Syndrome

  • 박원철 (울산대학교 의과대학 서울아산병원 내과학교실) ;
  • 김경덕 (울산대학교 의과대학 서울아산병원 내과학교실) ;
  • 신상효 (울산대학교 의과대학 서울아산병원 내과학교실) ;
  • 임재민 (울산대학교 의과대학 서울아산병원 내과학교실) ;
  • 배성진 (울산대학교 의과대학 서울아산병원 내과학교실) ;
  • 임주혁 (울산대학교 의과대학 서울아산병원 신경과학교실) ;
  • 임채만 (울산대학교 의과대학 서울아산병원 내과학교실) ;
  • 이상도 (울산대학교 의과대학 서울아산병원 내과학교실) ;
  • 김동순 (울산대학교 의과대학 서울아산병원 내과학교실) ;
  • 김원동 (울산대학교 의과대학 서울아산병원 내과학교실) ;
  • 김우성 (울산대학교 의과대학 서울아산병원 내과학교실)
  • Park, Won-Chul (Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Kim, Kyung-Duk (Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Shin, Sang-Hyo (Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Lim, Jae-Min (Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Bae, Sung-Jin (Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Im, Joo-Hyuk (Department of neurology, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Lim, Chae-Man (Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Lee, Sang-Do (Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Kim, Dong-Soon (Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Kim, Won-Dong (Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Kim, Woo-Sung (Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine)
  • 발행 : 2002.07.30

초록

Numb chin 증후군은 악성질환의 진행과 재발의 소견인 경우 외에도 암의 최초 증상으로 발현하기도 하며, 진단 후 대개 나쁜 경과와 예후를 보이는 것으로 알려져 있다. 저자들은 numb chin 증후군으로 발현한 비소세포폐암 1예를 경험하였기에 문헌고찰과 함께 보고하는 바이다.

Numb chin syndrome is a rare clinical manifestation, characterized by focal sensory loss and paresthesia of the chin. It is more often associated with cancer than with benign disorders, and can be the first manifestation of a cancer. A 60-year-old man presented with focal numbness of right chin and gingiva for 10 days. Chest computed tomograghy showed a 3 cm sized mass on the distal left main- stem bronchus. Squamous cell carcinoma was diagnosed on bronchoscopic biopsy. However, bony metastasis of mandible was not evident on reontgenogram, CT scan, bone scintigram and positron emission tomography. Despite the chemotherapy with three cycles of paclitaxel and cisplatinum, the cancer was progressed and pain on the right chin was developed 4 months later. Bone scintigram showed multiple bony metastasis including mandible. Here we report this case with a brief review of the appropriate literature.

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