Tuberculosis and Respiratory Diseases

The Korean Academy of Tuberculosis and Respiratory Diseases (대한결핵및호흡기학회)
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A Case of Primary Pulmonary Sarcoma with Morphologic Features of Malignant Fibrous Histiocytoma

악성 섬유조직구종 형태를 가진 원발성 폐육종 1예

  • Lee, Youn-Jeong (Department of Internal Medicine, Catholic University of Korea, School of Medicine) ;
  • Hur, Won-Haing (Department of Internal Medicine, Catholic University of Korea, School of Medicine) ;
  • Lo, Dae-Keun (Department of Internal Medicine, Catholic University of Korea, School of Medicine) ;
  • Kim, Seung-Joon (Department of Internal Medicine, Catholic University of Korea, School of Medicine) ;
  • Lee, Sook-Young (Department of Internal Medicine, Catholic University of Korea, School of Medicine) ;
  • Kim, Young-Kyoon (Department of Internal Medicine, Catholic University of Korea, School of Medicine) ;
  • Moon, Hwa-Sik (Department of Internal Medicine, Catholic University of Korea, School of Medicine) ;
  • Song, Jeong-Sup (Department of Internal Medicine, Catholic University of Korea, School of Medicine) ;
  • Park, Sung-Hak (Department of Internal Medicine, Catholic University of Korea, School of Medicine) ;
  • Park, Gyeong-Sin (Department of Clinical Pathology, Catholic University of Korea, School of Medicine) ;
  • Lee, Kyo-Young (Department of Clinical Pathology, Catholic University of Korea, School of Medicine)
  • 이연정 (가톨릭대학교 의과대학 내과학교실) ;
  • 허원행 (가톨릭대학교 의과대학 내과학교실) ;
  • 노대근 (가톨릭대학교 의과대학 내과학교실) ;
  • 김승준 (가톨릭대학교 의과대학 내과학교실) ;
  • 이숙영 (가톨릭대학교 의과대학 내과학교실) ;
  • 김영균 (가톨릭대학교 의과대학 내과학교실) ;
  • 문화식 (가톨릭대학교 의과대학 내과학교실) ;
  • 송정섭 (가톨릭대학교 의과대학 내과학교실) ;
  • 박성학 (가톨릭대학교 의과대학 내과학교실) ;
  • 박경신 (가톨릭대학교 의과대학 임상병리학교실) ;
  • 이교영 (가톨릭대학교 의과대학 임상병리학교실)
  • Published : 2002.02.28
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Abstract

A malignant fibrous histiocytoma is a malignant soft tissue neoplasm that occurs frequently in the metaphyseal ends of the long bones of adults. The lung is a common site for metastasis but it is a rare site for a primary malignant fibrous histiocytoma. Here we report a case of a primary malignant fibrous histiocytoma of the lung. The patient was a 53-year-old man who presented with a moderate amount of a left pleural effusion and an illdefined mass in the left lower lobe on a chest radiograph and a local invasion to the left 10th and 11th rib on chest CT. Under the strong suspicion of lung cancer with a pleural invasion, a serial diagnostic thoracentesis was performed. The cytologic examination of the pleural effusion revealed no malignant cells. Consequently, a thoracoscopic pleural biopsy was performed. The histological examination revealed slender spindle cells and scattered epitheloid cells arranged in a vague storiform or a whirling pattern. Immunohistochemicaily, the tumor cells tested positive for vimentin and negative for cytokeratin, desmin, CD 34 and PAS. These features were consistent with a malignant fibrous histiocytoma. This case is an unusual addition to the small number of published reports on a primary malignant fibrous histiocytoma of the lung.

저자들은 53세 남자환자에서 조직학적, 면역학적으로 악성 섬유조직구종의 형태를 가진 원발성 폐육종 1예를 경험하였기에 이를 문헌고찰과 함께 보고하는 바이다.

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