IMMUNE NETWORK
- 제2권2호
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- Pages.109-114
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- 2002
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- 1598-2629(pISSN)
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- 2092-6685(eISSN)
백서의 비장에서 화학적 교감신경절제가 뜸(구(灸))자극으로 유도된 면역변조에 미치는 영향
The Effect of Chemical Sympathectomy on Moxibustion-Induced Immunomodulation in the Rat Spleen
- 한재복 (경희대학교 대학원 동서의학과) ;
- 오상덕 (경희대학교 대학원 동서의학과) ;
- 이기석 (경희대학교 대학원 동서의학과) ;
- 최기순 (경희대학교 대학원 동서의학과) ;
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조영욱
(경희대학교 의과대학 생리학교실) ;
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안현종
(경희대학교 의과대학 미생물학교실) ;
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배현수
(경희대학교 한의과대학 생리학교실) ;
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민병일
(경희대학교 대학원 동서의학과)
- Han, Jae-Bok (Department of East-West Medicine, Graduate School, Kyung-Hee University) ;
- Oh, Sang-Duck (Department of East-West Medicine, Graduate School, Kyung-Hee University) ;
- Lee, Ki-Seok (Department of East-West Medicine, Graduate School, Kyung-Hee University) ;
- Choi, Ki-Soon (Department of East-West Medicine, Graduate School, Kyung-Hee University) ;
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Cho, Young-Wuk
(Department of Physiology, Medical College, Kyung-Hee University) ;
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Ahn, Hyun-Jong
(Department of Microbiology, Medical College, Kyung-Hee University) ;
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Bae, Hyun-Soo
(Department of Physiology, Oriental Medical College, Kyung-Hee University) ;
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Min, Byung-Il
(Department of East-West Medicine, Graduate School, Kyung-Hee University)
- 발행 : 2002.06.30
초록
Background: To investigate the role of sympathetic nervous system (SNS) in moxibustion-induced immunomodulation, the effects of chemical sympathectomy on moxibustion-induced changes in splenic NK cell cytotoxicity, T and B cell proliferation were studied in Sprague-Dawley male rats. Methods: Chemical sympathectomy was achieved with intraperitoneal injection of 6-hydroxydopamine 50 mg/kg/day for 3 successive days. Direct moxibustion (6-minute interval, 9 moxa ball, each of which weighing 0.007 g and burning for 40 seconds) was applied on unilateral anterior tibial muscle region where Zusanli (ST36) acupoint is located, once a day for 7 successive days. NK cell cytotoxicity was measured by