천막상부 뇌졸중에서 소뇌의 혈역학 변화 -Dynamic Susceptibility Contrast MR 영상을 이용한-

Effect of Supratentorial Stroke on Cerebellar Hemodynamic Parameters - Assessment by Dynamic Susceptibility Contrast MR Imaging

  • 한시령 (가톨릭대학교 의과대학 신경과학교실) ;
  • 김범수 (가톨릭대학교 의과대학 방사선과학교실) ;
  • 곽태호 (가톨릭대학교 의과대학 신경과학교실) ;
  • 최영빈 (가톨릭대학교 의과대학 신경과학교실) ;
  • 김영인 (가톨릭대학교 의과대학 신경과학교실)
  • Han, Si-Ryung (Department of Neurology, College of Medicine, The Catholic University of Korea) ;
  • Kim, Bum-Soo (Department of Radiology, College of Medicine, The Catholic University of Korea) ;
  • Guak, Tae-Ho (Department of Neurology, College of Medicine, The Catholic University of Korea) ;
  • Choi, Young-Bin (Department of Neurology, College of Medicine, The Catholic University of Korea) ;
  • Kim, Yeong-In (Department of Neurology, College of Medicine, The Catholic University of Korea)
  • 발행 : 2002.05.01

초록

Background & Purpose : Dynamic susceptibility contrast MR imaging, one method of perfusion MRI, was developed to define cerebral hemodynamic status with good anatomical resolution. The authors investigated hemodynamic parameters using this imaging method, in an effort to identify hemodynamic changes on the remote crossed cerebellum of patients with a supratentorial infarct. Methods : Dynamic susceptibility contrast MR imaging was performed in 15 patients with only unilateral supratentorial infarcts. Imaging was obtained at the anatomic level of the cerebellum. rCBF, rCBV, MTT and TP were determined over both cerebellar hemispheres of interest. Results : The rCBF and rCBV values of the contralateral cerebellar hemisphere were significantly more decreased than those of the ipsilateral cerebellar hemisphere in 12 patients(p=0.028, 0.033). MTT and TP values of the contralateral and ipsilateral cerebellar hemispheres didn't reveal any differences(p=0.130, 0.121). Conclusions : The results of this work suggest that the region which are remote from the ischemic brain lesion shows no changes of MTT or TP but show decrease of rCBF and rCBV, mean to diaschisis, it also demonstrates that perfusion MRI is an easily available method to evaluate the hemodynamic status of the brain.

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