Journal of Acupuncture Research
- Volume 19 Issue 5
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- Pages.92-111
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- 2002
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- 2586-288X(pISSN)
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- 2586-2898(eISSN)
Effects of Aqua-Acupuncture of Carthami Flos(GV15) on the Changes of Cerebral Hemodynamics in Rats
아문(瘂門)(GV15)의 홍화약침(紅花藥針)이 백서(白鼠)의 뇌혈류역학(腦血流力學) 변동(變動)에 미치는 영향(影響)
- Ahn, Young-sun (Department of Acupuncture & Moxibustion, College of Oriental Medicine Dong-Shin University) ;
- Wei, Tung-shuen (Department of Acupuncture & Moxibustion, College of Oriental Medicine Dong-Shin University) ;
- Cho, Myung-rae (Department of Acupuncture & Moxibustion, College of Oriental Medicine Dong-Shin University) ;
- Chae, Woo-seok (Department of Acupuncture & Moxibustion, College of Oriental Medicine Dong-Shin University) ;
- Yun, Yeo-choong (Department of Acupuncture & Moxibustion, College of Oriental Medicine Dong-Shin University)
- 안영선 (동신대학교 한의과대학 침구학교실) ;
- 위통순 (동신대학교 한의과대학 침구학교실) ;
- 조명래 (동신대학교 한의과대학 침구학교실) ;
- 채우석 (동신대학교 한의과대학 침구학교실) ;
- 윤여충 (동신대학교 한의과대학 침구학교실)
- Received : 2002.09.01
- Accepted : 2002.09.14
- Published : 2002.10.20
Abstract
Objective : Carthami Flos has been used as a herb to promote blood circulation to remove blood stasis in oriental medicine for many centuries, and Amun(GV15) has been used as a meridian point to treat apoplexy etc. To investigate treatment of cerevral vascular disease(CVA) by promoting blood circulation and removing blood stasis(活血化瘀法), we observed the experimental effects and mechanism of auqa-acupunture of Carthami Flos(ACF) injected into GV15 on cerevral hemodynamics and cardiovascular system of rats. Method : Aqua-acupuncture of Carthami Flos(ACF) was injected into GV15, and then we investigated experimental effects and mechanism of ACF on the cerebral hemodynamics[regional cerebral blood flow(rCBF), pial arterial diameter(PAD), meal arterial blood pressure(MABP)] and cardiovascular system[cardiac muscle contractile force(CMF), heart rate(HR)I by pretreatment with methylene blue(MTB) and indomethacin(IDN). The changes in rCBF, MABP, CMF and HR were tested by Laser Doppler Flowmetry(LDF), and the changes in PAD was determinated by video microscopy methods and video analyzer. Results :The results were as follows in normal rats ; The changes of rCBF and PAD were significantly increased by ACF(
Keywords
- auqa-acupunture of Carthami Flos(ACF);
- Amun(GV15);
- methylene blue(MTB) indomethacin(IDN);
- regional cerebral blood flow(rCBF);
- pial arterial diameter(PAD);
- meal arterial blood pressure(MABP)