Pediatric Infection and Vaccine

The Korean Society of Pediatric Infectious Diseases (대한소아감염학회)
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A Case of Epstein-Barr Virus-Associated Hemophagocytic Syndrome with Ascites

복수를 동반한 Epstein-Barr바이러스 연관성 혈구탐식증후군 1례

  • Choi, Ye-Na (Department of Pediatrics, College of Medicine, Yonsei University) ;
  • Jang, Gwang-Cheon (Department of Pediatrics, College of Medicine, Yonsei University) ;
  • Kim, Dong-Soo (Department of Pediatrics, College of Medicine, Yonsei University) ;
  • Park, Young-Nyun (Department of Pathology, College of Medicine, Yonsei University)
  • 최예나 (연세대학교 의과대학 소아과학교실) ;
  • 장광천 (연세대학교 의과대학 소아과학교실) ;
  • 김동수 (연세대학교 의과대학 소아과학교실) ;
  • 박영년 (연세대학교 의과대학 병리학교실)
  • Published : 2002.05.31
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Abstract

Hemophagocytic syndrome(HPS) has four subgroup, sporadic disorder, associated with acute infection, familial form seen in children, and associated with malignant disorders, immunodeficiencies, defective leukocyte function. Histologically, Hemopoietic cells are actively ingested by moncytes/macrophages in various organs, including lymph nodes, bone marrow, liver, and spleen. Epstein-Barr virus(EBV) is now thought to be one of the major causes for the virus-associated hemophagocytic syndrome(VAHS). Epstein-Barr(EB) virus infection is common, with up to 90% of individuals demonstrating positive titiers by age 20. Although elevated liver function tests commonly occur, severe hepatitis is rare. Only seven cases of ascites complicating Epstein-Barr infection are reported, but none clearly demonstrate the abscence of other causes of hepatic dysfunction. We are reporting a case of Epstein-Barr Virus-associated hemophagocytic syndrome with ascites.

저자들은 내원 1개월 전부터의 고열 복통을 주소로 전원되어 복수를 동반한 EBV 연관성 VAHS로 진단된 1례를 경험하였기에 문헌고찰과 함께 보고하는 바이다.

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