YAKHAK HOEJI (약학회지)

The Pharmaceutical Society of Korea (대한약학회)
권호 표지

Optimal Synthesis Conditions of Barium Sulfate

황산바륨의 최적합성조건

  • 신화우 (원광대학교 약학대학) ;
  • 최광식 (국립독성연구소 특수 독성부)
  • Published : 2002.10.01
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Abstract

Optimal synthetic conditions of barium sulfate were investigated from the viewpoint of yield and bulkiness according to a randomized complete block design proposed by Box and Wilson. Barium chloride and Sodium sulfate were utilized as reactants in order to prepare barium sulfate in this study. The optimum Synthesis conditions of barium sulfate obtained from this study are as follows; Reactant temperature; 60~75$^{\circ}C$ (viewpoint of yield) and 60~71$^{\circ}C$ (viewpoint of bulkiness). Concentration of two reactants; 12.7~14.4％ (viewpoint of yield) and 5~10.5％ (viewpoint of bulkiness). Mole ratio of two reactants, [BaCl$_2$]/[Na$_2$SO$_4$]; 1.62~1.96 (viewpoint of yield) and 2.0 (viewpoint of bulkiness). Reacting time; 13~15 minutes (viewpoint of yield) and 12~14 minutes (viewpoint of bulkiness). Drying temperature of product; 86~10$0^{\circ}C$ (viewpoint of yield) and 6$0^{\circ}C$ (viewpoint of bulkiness).

Keywords

References

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