Blood Viscosity Measurements Using a Pressure-Scanning Capillary Viscometer

  • Sehyun Shin (School of Mechanical Engineering, Kyungpook National University) ;
  • Keum, Do-Young (School of Mechanical Engineering, Kyungpook National University) ;
  • Ku, Yun-Hee (School of Mechanical Engineering, Kyungpook National University)
  • Published : 2002.12.01

Abstract

A previously designed capillary viscometer with measuring differential pressure was modified to measure the viscosity of non-Newtonian fluids including unadulterated blood continuously over numerous shear rates in a single measurement. Because of unavoidable experimental noise and a limited number of data, the previous capillary viscometer experienced an inaccuracy and could not directly determine a viscosity without an iterative calculation. However, in the present measurement there are numerous data available near the point of interest so that the numeric value of the derivative, d(In Q)/d(In Q$\sub$w/), is no longer sensitive to the method of differentiation. In addition, relatively low and wide shear rate viscosity measurements were possible because of the present precision pressure-scanning method with respect to time. For aqueous polymer solutions, excellent agreement was found between the results from the pressure-scanning capillary viscometer and those from a commercially available rotating viscometer. In addition, the pressure-scanning capillary viscometer measured the viscosity of unadulterated whole blood without adding any anticoagulants.

Keywords

References

  1. Bird, R. B., Amstrong, R. C. and Hassager, O., 1987, Dynamics of Polymeric Liquids, Vol. 1, New York: John Wiley & Son
  2. Chandler, W. L. and Schmer, G., 1986, 'Evaulation of a New Dynamic Viscometer for Measuring the Viscosity of Whole Blood and Plasma,' Clin. Chern., Vol. 32, pp. 505-507
  3. Dintenfass L., 1969, 'Blood Rheology in Pathogenesis of the Coronary Heart Deseases,' Am. Hearl J., Vol. 77, pp. 139-147 https://doi.org/10.1016/0002-8703(69)90139-2
  4. Eckmann, D. M., Bowers, S., Stecker M. and Cheung, A. T., 2000, 'Hematocrit, Volume Expander, Temperature, Ans Shear Rate Effect Pn Blood Viscosity,' Anesth Analg, Vol. 91, pp. 539- 545 https://doi.org/10.1097/00000539-200009000-00007
  5. Fossum, E., Roieggen A. and Moan, A., 1997, 'Whole Blood Viscosity, Blood Pressure and Cardiovascular Risk Factors in Healthy Blood Donors,' Blood Press., Vol. 6, pp. 161-165 https://doi.org/10.3109/08037059709061932
  6. Kensey, K. R. and Cho, Y. L, 1992, 'Protective Adaptation Hypothesis as the Etiology of Atherosclerosis,' J. Invasive Cardiol, Vol. 4, pp.448-458
  7. Lide, D. R. (Ed), 1994, CRC handbook of chemistry and physics, 75th ed. CRC Press, Boca Raton, F. L.
  8. Macosko, C. W., 1993, Rheology: Principles, Measurements, and Applications, VCH, New York
  9. Nguyen, Y. T., Vu, T. D., Wong, H. K. and Yeow, Y. L., 1999, 'Solving the Inverse Problem of Capillary Viscometry by Tikhonov Regularization,' J. Non-Newtonian Fluid Mech., Vol. 87, p.103 https://doi.org/10.1016/S0377-0257(99)00057-9
  10. Ogawa, K., Okawara S., lto, S. and Taniguchi, K., 1991, 'Blood Viscometer with Vacuum Glass Suction Tube and Needle,' J. Chemical Eng. of Japan, Vol. 24, p. 215 https://doi.org/10.1252/jcej.24.215
  11. Reinhart, W. H., Haeberli, A., Stark, J., Straub, P. W., 1990, 'Influence of Blood Withdrawal and Anticoagulant on Clotting Activity, Hematologic Data, and Certain Rheologic Measurements,' J. Lab. Clinical Med., Vol. 115, pp. 98-103
  12. Shin, S. and Keum, D. Y., 2002a, 'Continuous V iscosity Measurement of Polymer Solutions over a Range of Shear Rates Using a Mass-Detecting Capillary Viscometer,' KSME Int. J., Vol. 16, pp.255-261
  13. Shin, S. and Keum, D. Y., 2002b, 'A new MassDetecting Capillary Viscometer,' Biosensor and Bioelectronics, Vol. 17, pp. 383 - 388 https://doi.org/10.1016/S0956-5663(01)00314-1
  14. Singh, M. and Coulter, A., 1973, 'Rheology of Blood Effect of Dilution with Various Dextrans,' Microvasc. Res., Vol. 5, pp. 123-135 https://doi.org/10.1016/0026-2862(73)90063-0