Environmental Mutagens and Carcinogens (한국환경성돌연변이발암원학회지)
- Volume 22 Issue 2
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- Pages.65-69
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- 2002
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- 1225-6307(pISSN)
Biodistribution of [S-35] Labeled Antisense Oligodeoxynucleotides Increased Tumor Targeting With Microsphere Coinjection
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Choe, Jae-Gol
(Department of Nuclear Medicine, Korea University Medical College) ;
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Park, Gil-Hong
(Department of Biochemistry and Molecular Biology, Korea University Medical College) ;
- Claudio Nastruzzi (Department of Pharmaceutical Science, University of Ferrara) ;
- Yoon S. Cho-Chung (Cellular Biochemistry Section, Laboratory of Tumor Immunology and Biology, National Cancer Institute) ;
- Kim, Meyoung-Kon (Department of Biochemistry and Molecular Biology, Korea University Medical College)
- Published : 2002.06.01
Abstract
To elucidate the effect of microsphere coinjection on the administration of oligodeoxynucleotides (ODN), we have investigated biodistribution of [S-35]-labeled antisense ODN targeted to cAMP-dependent protein kinase (PKA) RI-