Childhood Kidney Diseases
- Volume 6 Issue 1
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- Pages.85-91
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- 2002
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- 2384-0242(pISSN)
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- 2384-0250(eISSN)
Antifibrotic Effects of Phosphodiesterase (PDE) Inhibitor in Experimental Interstitial Fibrosis induced by Unilateral Ureteral Obstruction.
일측성 요로폐쇄에 의한 실험적 신 간질 섬유화에서 Phosphodiesterase(PDE) 억제제의 항 섬유화 작용
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Ha Il Soo
(Department of Pediatrics, Seoul National University College of Medicine) ;
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Um Eun Young
(Department of Pediatrics, Seoul National University College of Medicine) ;
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Kang Hee-Gyung
(Department of Pediatrics, Seoul National University College of Medicine) ;
- Hahn Hye Won (Department of Pediatrics, Seoul National University College of Medicine) ;
- Park Hye Won (Department of Pediatrics, Seoul National University College of Medicine) ;
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Cheong Hae Il
(Department of Pediatrics, Seoul National University College of Medicine) ;
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Choi Yong
(Department of Pediatrics, Seoul National University College of Medicine)
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하일수
(서울대학교 의과대학 소아과학교실) ;
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엄은영
(서울대학교 의과대학 소아과학교실) ;
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강희경
(서울대학교 의과대학 소아과학교실) ;
- 한혜원 (서울대학교 의과대학 소아과학교실) ;
- 박혜원 (서울대학교 의과대학 소아과학교실) ;
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정해일
(서울대학교 의과대학 소아과학교실) ;
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최용
(서울대학교 의과대학 소아과학교실)
- Published : 2002.04.01
Abstract
Purpose: Phosphodiesterase (PDE) inhibitor increases the cellular content of cAMP, and cAMP suppresses connective tissue growth factor (CTGF) expression induced by TGF-
서 론 : Phosphodiesterase (PDE) 억제제는 세포내 cAMP를 증가시키며, cAMP는 TGF-
Keywords
- Phosphodiesterase (PDE) inhibitor;
- Cilostazol;
- Dipyridamole;
- Interstitial fibrosis;
- Unilateral ureteral obstruction;
- Rat