통증 신호 전달에 있어서 ATP의 역할

The Role of the ATP in the Pain Signal Transmission

  • 구현모 (대구대학교 대학원 재활과학과 물리치료) ;
  • 남기원 (대구대학교 대학원 재활과학과 물리치료) ;
  • 김진상 (대구대학교 물리치료학과)
  • Koo Hyun-Mo (Department of Physical Therapy, Graduate School of Rehabilitation Science, Daegu University) ;
  • Nam Ki-Won (Department of Physical Therapy, Graduate School of Rehabilitation Science, Daegu University) ;
  • Kim Jin-sang (Department of Physical Therapy, Daegu University)
  • 발행 : 2002.12.01

초록

A role for ATP in nociception and pain induction was proposed. ATP-gated P2X ion channel receptors are localized throughout the nervous system and have been identified on neurons which participate in conduction of nociceptive information from the periphery to central nervous system. We consider the role of ATP as a peripheral activator of nociceptive sensory neuron via ATP-gated ion channels.

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