The Effect of Ultrasound on $TGF-\beta$ Expression in the Injured Achilles Tendons of Rats

초음파가 흰쥐 아킬레스건 손상부위의 $TGF-\beta$발현에 미치는 영향

  • Yoon Soo-Jin (Major in Physical Therapy, Graduate School of Rehabilitation Science, Daegu University)
  • 윤수진 (대구대학교 재활과학대학원 물리치료전공)
  • Published : 2002.09.01

Abstract

This study was performed to investigate the effect of ultrasound irradiation on $TGF-\beta_1$ expression in the surgically injured achilles tendons of rats. The results of this study were as following: 1. The control group (3 days after injury) expressed little immunoreactivity for $TGF-\beta_1$. 2. In the experimental groups, $TGF-\beta_1$ immunoreactivity of group 11(applied US for 3 days) was increased markedly than that of group 1(applied US for 1 day). 3, The experimental group 11(applied US for 3 days) expressed higher immunoreactivity for $TGF-\beta_1$ than control group. These findings suggest that ultrasound irradiation on the injured Achilles tendon may be of benefit such as increasing $TGF-\beta$ release in the inflammatory phase of heal ins process.

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