생약학회지 (Korean Journal of Pharmacognosy)

한국생약학회 (The Korean Society of Pharmacognosy)
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생약의 VHR Dual - Specificity Protein Tyrosine Phosphatase (DS-PTPase) 저해 활성 검색

Screening of the Inhibitory Activity of Medicinal Plants against VHR Dual-Specificity Protein Tyrosine Phosphatase (DS- PTPase)

  • Lee, Myung-Sun (Korea Research Institute of Bioscience and Biotechnology) ;
  • Bae, Eun-Young (Korea Research Institute of Bioscience and Biotechnology) ;
  • Oh, Won-Keun (Korea Research Institute of Bioscience and Biotechnology) ;
  • Ahn, Soon-Cheol (Korea Research Institute of Bioscience and Biotechnology) ;
  • Kim, Bo-Yeon (Korea Research Institute of Bioscience and Biotechnology) ;
  • Sohn, Cheon-Bae (Department of Food and Nutrition, Chungnam National University) ;
  • Ahn, Jong-Seog (Korea Research Institute of Bioscience and Biotechnology)
  • 발행 : 2002.03.30
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초록

The methanol extracts of 162 herbal medicines were screened for the inhibitory activity against VHR dualspecificity protein tyrosine phosphatase (DS-PTPase). Seventeen medicinal plants, Scutellaria baicalensis, Cuscuta chinensis, Caesalpinia sappan, Arecae pericarpium, Rubus coreanus, Machilus thunbergii, Amsonia elliptica Cinnamomum cassia, Arisaema erubescens, Pueraria thunbergiana, Dendrobium moniliforme, Mentha arvensis, Peucedanum japonicum, Salvia miltiorrhiza, Leonurus sibiricus, Siegesbeckia orientalis, Prunella vulgaris showed potent VHR DS-PTPase inhibitory activity.

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참고문헌

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