A Flavone Glycoside from Angelica gigas Roots

  • Lee, Sang-Hyun (Natural Products Research Institute, Seoul National University) ;
  • Kang, Sam-Sik (Natural Products Research Institute, Seoul National University) ;
  • Shin, Kuk-Hyun (Natural Products Research Institute, Seoul National University)
  • Published : 2002.12.01

Abstract

A flavone glycoside was isolated from the roots of Angelica gigas (Umbelliferae) and identified as diosmin $[diosmetin-7-O-{\alpha}-{_L}-rhamnopyranosyl \;(1{\rightarrow}6)-{\beta}-{_D}-glucopyranoside]$ by spectroscopic methods. This is the first report of a flavone gylcoside from Angelica species.

Keywords

References

  1. Chi, H-J. and Kim, H. S., Studies on the essential oils of plants of Angelica genus in Korea (I). Essential oils of Angelicae gigantis Radix. Kor. J. Pharmacogn. 19, 239-247 (1988)
  2. Chi, H-J., Studies on the components of Umbelliferous plants in Korea (IV). Yakhak Hoeji 13, 47-50 (1969)
  3. Choi, Y. E., Ahn, H. and Ryu, J-H., Polyacetylenes from Angelica gigas and their inhibitory activity on nitric oxide synthesis in activated macrophages. Biol. Pharm. Bull. 23, 884-886 (2000) https://doi.org/10.1248/bpb.23.884
  4. Han, Y. N., Noh, D. B. and Han, D. S. Studies on the monoamine oxidase inhibitors of medicinal plants I. Isolation of MAO-B inhibitors from Chrysanthemum indicum. Arch. Pharm. Res. 10, 142-147 (1987) https://doi.org/10.1007/BF02857780
  5. Jung, D. J., Porzel, A. and Huneck, S., Gigasol and other coumarins from Angelica gigas. Phytochemistry 30, 710-712 (1991) https://doi.org/10.1016/0031-9422(91)83763-B
  6. Kang, S. S., Um, B. H., Kim, J. S. and Ahn, B. T., Isolation of flavonoids from Evodiae Fructus. Kor. J. Pharmacogn. 28, 9-14 (1997)
  7. Konoshima, M., Chi, H-J. and Hata, K., Coumarins from the root of AngeIica gigas Nskai Chem. Pharm. Bull. 16, 1139-1140 (1968) https://doi.org/10.1248/cpb.16.1139
  8. Lee, S., Kang, S. S. and Shin, K. H., Coumarins and a pyrimidine from Angelica gigas roots. Nat. Prod. Sci. 8, 58-61 (2002)
  9. Pachaly, P., Treitner, A. and Sin, K. S., Neue Cumaringlykoside aus Angelica gigas. Pharmazie 51, 57-61 (1996)
  10. Ryu, K. S., Hong, N. D., Kim, N. J. and Kong, Y. Y., Studies on the coumarin constituents of the root of Angelica gigas Nakai. Isolation of decursinol angelate and assay of decursin angelate and decursm. Kor. J. Pharmacogn. 21, 64-68 (1990)
  11. Son, K. H., Kim, J. S., Kang, S. S., Kim, H. P. and Chang, H. W. Isolation of flavonoids from Lonicera japonica. Kor. J. Pharmacogn. 25, 24-27 (1994)
  12. Yook, C. S., Coloured medicinal plants of Korea, Academy Book Co. Seoul, Korea, 1990, p. 390