The Journal of Pediatrics of Korean Medicine (대한한방소아과학회지)

The Association of Korean Oriental Pediatrics (대한한방소아과학회)
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Effect of Sunbangpaedoktang on the Cytokine Secretory Function of Monocyte Isolated and Cultured from Peripheral Blood of AD Patients

선방패독탕(仙方敗毒湯)이 아토피 피부염 환자 단핵세포의 Cytokine 분비능에 미치는 영향

  • Shin, Dong-Gil (Dept. of Oriental Pediatrics, College of Oriental Medicine, Kyung Hee University) ;
  • Kim, Woo-Yeon (AAHAE Oriental Medical Clinic) ;
  • Lee, Jin-Yong (Dept. of Oriental Pediatrics, College of Oriental Medicine, Kyung Hee University) ;
  • Kim, Deog-Kon (Dept. of Oriental Pediatrics, College of Oriental Medicine, Kyung Hee University)
  • 신동길 (경희대학교 한의과대학 소아과교실) ;
  • 김우연 (수원 아해한의원) ;
  • 이진용 (경희대학교 한의과대학 소아과교실) ;
  • 김덕곤 (경희대학교 한의과대학 소아과교실)
  • Published : 2002.08.15
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Abstract

Effect of Sunbangpaedoktang, which has been used for atopic dermatitis(AD), on the cytokine secretory function of monocyte, which was isolated and cultured from peripheral blood of AD patients, were evaluated. The results were as follows: 1. In AD patients, Sunbangpaedoktang exhibits statistically significant inhibitory effect on IL-4. 2. In AD patients, Sunbangpaedoktang exhibits statistically significant inhibitory effect on IL-5(p<0.05). 3. In AD patients, Sunbangpaedoktang exhibits statistically significant inhibitory effect on $IFN-{\gamma}$(p<0.01). 4. In sample group, comparing the cytokine concentration change rate of AD patients with that of NAD patients IL-4 AD patients exhibits statistically significant decrease(p<0.05).

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