Korean Journal of Biological Psychiatry (생물정신의학)

The Korean Society of Biological Psychiatry (대한생물정신의학회)
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Three Cases of Mirtazapine Induced Akathisia

Mirtazapine 사용후 정좌불능증(Akathisia)을 보인 환자 3례

  • Lee, Seung-Hwan (Department of Neuropsychiatry, College of medicine, Inje University) ;
  • Nam, Min (Department of Neuropsychiatry, College of medicine, Inje University) ;
  • Chung, Young-Cho (Department of Neuropsychiatry, College of medicine, Inje University)
  • 이승환 (인제대학교 의과대학 신경정신과학교실) ;
  • 남민 (인제대학교 의과대학 신경정신과학교실) ;
  • 정영조 (인제대학교 의과대학 신경정신과학교실)
  • Published : 2001.06.30
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Abstract

The mirtazapine is a relatively new antidepressant that has noradrenergic and specific serotonin antagonist action(NaSSAs). This has been known as one of the most safest drugs because of its few side effects. Until now, there have been only one case report that mirtazapine causes a EPS side effect(restless leg syndrome). But the peculiar mechanism of this drug makes it impossible to explain the exact reasons why the mirtazapine could induce EPS symptoms. Authors observed three cases of mirtazapine induced akathisia. We could not explain the phenomenon the other way except akathisia. So here we presents the three case of mirtazapine induced akathisia and a few possible hypothesis of this phenomenon.

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