Tuberculosis and Respiratory Diseases

The Korean Academy of Tuberculosis and Respiratory Diseases (대한결핵및호흡기학회)
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A Case of Churg-Strauss Syndrome with Bilateral Pleural Effusions

양측성 흉막 삼출증을 동반한 Churg-Strauss 증후군 1예

  • Kim, Min-Su (Department of Medicine, Institute of Medical Science, Keimyung University School of Medicine) ;
  • Lee, Seung-Hyun (Department of Medicine, Institute of Medical Science, Keimyung University School of Medicine) ;
  • Han, Seung-Beom (Department of Medicine, Institute of Medical Science, Keimyung University School of Medicine) ;
  • Kwon, Kun-Young (Department of Pathology, Institute of Medical Science, Keimyung University School of Medicine) ;
  • Jeon, Young-June (Department of Medicine, Institute of Medical Science, Keimyung University School of Medicine)
  • 김민수 (계명대학교 의과대학 내과학교실, 의과학 연구소) ;
  • 이승현 (계명대학교 의과대학 내과학교실, 의과학 연구소) ;
  • 한승범 (계명대학교 의과대학 내과학교실, 의과학 연구소) ;
  • 권건영 (계명대학교 의과대학 병리학교실, 의과학 연구소) ;
  • 전영준 (계명대학교 의과대학 내과학교실, 의과학 연구소)
  • Published : 2001.02.28
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Abstract

A 26-year-old man with a one-year history of asthma and sinusitis presented with bilateral pleural effusions, patch basilar infiltrates on a chest x-ray and a pericardial effusion on an echocardiogram. The peripheral blood showed marked eosinophilia. An obstructive pattern was also observed during the pulmonary fuction test, which was responsive to bronchodilator inhalation. Nerve conduction studies showed right sural neuropathy. Thoracentesis yielded an acidotic exudative effusion with low glucose, low $C_3$ and eosinophilia. An open lung biopsy revealed an eosinophilic interstitial pneumonitis associated with a necrotizing eosinophilic vasculitis, and granulomatous inflammation foci. In the literature, pleural effusions were reported in 29 percent of Churg-Strauss patients, but the number of effusions was low and their characteristics have not been well described. This report describes the characteristic findings of pleural fluid and its histologic features in a case of classical Churg-Strauss syndrome.

저자들은 비염과 기관지 천식의 병력이 있으면서 열감, 설사, 신경염 증상과 함께 양측성 흉막액과 심낭액 그리고 페침윤을 보인 환자에서 흉박액 성분검사상 저당, 산성 삼출액 소견과, 폐조직 검사상 호산구 침윤과 혈관염 및 육아종성 염증 소견을 보인 Churg-Strauss 증후군 1예를 경험하였기에 이에 문헌고찰과 함께 보고하는 바이다.

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