Journal of Korean Neurosurgical Society

The Korean Neurosurgical Society (대한신경외과학회)
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A Case of Brain Abscess in a Patient with Primary Mucociliary Transport Failure - Case Report -

원발성 점액섬모 이송기능 장애 환자에서 발생한 뇌농양 - 증례보고 -

  • Yoon, Sung Hoon (Department of Neurosurgery, The Catholic University, College of Medicine, Daejeon St. Mary's Hospital) ;
  • Lee, Hyung Jin (Department of Neurosurgery, The Catholic University, College of Medicine, Daejeon St. Mary's Hospital) ;
  • Yi, Jin Seok (Department of Neurosurgery, The Catholic University, College of Medicine, Daejeon St. Mary's Hospital) ;
  • Yang, Ji Ho (Department of Neurosurgery, The Catholic University, College of Medicine, Daejeon St. Mary's Hospital) ;
  • Lee, Il Woo (Department of Neurosurgery, The Catholic University, College of Medicine, Daejeon St. Mary's Hospital) ;
  • Song, Kyu Sang (Department of Anatomy, The Chungnam University, College of Medicine) ;
  • Kang, Joon Ki (Department of Neurosurgery, The Catholic University, College of Medicine, Daejeon St. Mary's Hospital)
  • 윤성훈 (가톨릭대학교 의과대학 대전성모병원 신경외과학교실) ;
  • 이형진 (가톨릭대학교 의과대학 대전성모병원 신경외과학교실) ;
  • 이진석 (가톨릭대학교 의과대학 대전성모병원 신경외과학교실) ;
  • 양지호 (가톨릭대학교 의과대학 대전성모병원 신경외과학교실) ;
  • 이일우 (가톨릭대학교 의과대학 대전성모병원 신경외과학교실) ;
  • 송규상 (충남대학교 의과대학 해부학교실) ;
  • 강준기 (가톨릭대학교 의과대학 대전성모병원 신경외과학교실)
  • Received : 2001.05.04
  • Accepted : 2001.11.11
  • Published : 2001.12.28
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Abstract

The authors present a case of brain abscess in a patient with primary mucociliary transport failure. Primary mucociliary transport failure is unfamiliar term to neurosurgeon. It encompasses three hereditary disorders, that is, primary ciliary dyskinesia, cystic fibrosis and Young's syndrome. Clinical manifestations in these disorders appear to overlap each other, e.g., male infertility and chronic sinopulmonary infections. These are characterized by ciliary dysfunction or abnormality of mucus secretion therefore recurrent infection occurs in organs containing the mucociliary transport system. Major causes of non-traumatic brain abscess are sinusitis and pulmonary infection. So the possibility of brain abscess is much higher if mucociliary transport failure exists. Especially, young patients who have brain abscess coexisting with chronic sinopulmonary infection should be considered primary mucociliary transport failure.

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