Journal of Korean Neurosurgical Society
- Volume 30 Issue 12
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- Pages.1381-1387
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- 2001
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- 2005-3711(pISSN)
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- 1598-7876(eISSN)
Intracranial Endodermal Sinus Tumor
두개강내 내배엽성 동종양(Endodermal Sinus Tumor)
- Lim, Yong Chull (Department of Neurosurgery, Ajou University School of Medicine) ;
- Cho, Kyung Gi (Department of Neurosurgery, Ajou University School of Medicine) ;
- Lee, Seong Un (Department of Neurosurgery, Ajou University School of Medicine) ;
- Park, Han Jun (Department of Neurosurgery, Ajou University School of Medicine) ;
- Shin, Yong Sam (Department of Neurosurgery, Ajou University School of Medicine) ;
- Yun, Soo Han (Department of Neurosurgery, Ajou University School of Medicine) ;
- Cho, Ki Hong (Department of Neurosurgery, Ajou University School of Medicine)
- 임용철 (아주대학교 의과대학 신경외과학교실) ;
- 조경기 (아주대학교 의과대학 신경외과학교실) ;
- 이성운 (아주대학교 의과대학 신경외과학교실) ;
- 박한준 (아주대학교 의과대학 신경외과학교실) ;
- 신용삼 (아주대학교 의과대학 신경외과학교실) ;
- 윤수한 (아주대학교 의과대학 신경외과학교실) ;
- 조기홍 (아주대학교 의과대학 신경외과학교실)
- Received : 2001.07.03
- Accepted : 2001.11.16
- Published : 2001.12.28
Abstract
Objective : Endodermal sinus tumor or yolk sac tumor is an uncommon malignant germ-cell neoplasm. This tumor was originally described as a germ cell tumor of the ovary or the testis. Intracranial endodermal sinus tumor is extremely rare and usually develop in the pineal or suprasellar regions. The authors evaluated the effect of adjuvant therapy(chemotherapy combined with radiotherapy) and radical removal of intracranial endodermal sinus tumors. Material and Methods : Between 1996 and 2001, four patients of intracranial endodermal sinus tumor were diagnosed with tumor marker(AFP) and biopsy. Three patients were treated with surgical removal and chemotherapy with cisplatin(