Journal of Korean Neurosurgical Society
- Volume 30 Issue 5
- /
- Pages.611-621
- /
- 2001
- /
- 2005-3711(pISSN)
- /
- 1598-7876(eISSN)
Endocrinological Results of the Transsphenoidal Microsurgery for Cushing's Disease
쿠싱병에 대한 경접형동접근법의 내분비학적 결과
- Kim, Joon Soo (Department of Neurological Surgery, Asan Medical Center, College of Medicine, University of Ulsan) ;
- Kim, Chang Jin (Department of Neurological Surgery, Asan Medical Center, College of Medicine, University of Ulsan) ;
- Ha, Sang Soo (Department of Neurological Surgery, Asan Medical Center, College of Medicine, University of Ulsan) ;
- Kim, Jung Hoon (Department of Neurological Surgery, Asan Medical Center, College of Medicine, University of Ulsan) ;
- Lee, Jung Gyo (Department of Neurological Surgery, Asan Medical Center, College of Medicine, University of Ulsan) ;
- Kwun, Byung Duk (Department of Neurological Surgery, Asan Medical Center, College of Medicine, University of Ulsan) ;
- Hong, Sung Kwan (Department of Endocrinology, Asan Medical Center, College of Medicine, University of Ulsan) ;
-
Lee, Ki Up
(Department of Endocrinology, Asan Medical Center, College of Medicine, University of Ulsan) ;
- Lee, Bong Jae (Department of Otolaryngology, Asan Medical Center, College of Medicine, University of Ulsan) ;
- Kim, Yong Jae (Department of Otolaryngology, Asan Medical Center, College of Medicine, University of Ulsan) ;
-
Choi, Choong Kon
(Department of Diagnostic Radiology, Asan Medical Center, College of Medicine, University of Ulsan) ;
- Lee, Ho Gyu (Department of Diagnostic Radiology, Asan Medical Center, College of Medicine, University of Ulsan)
- 김준수 (울산대학교 의과대학 서울중앙병원 신경외과학교실) ;
- 김창진 (울산대학교 의과대학 서울중앙병원 신경외과학교실) ;
- 하상수 (울산대학교 의과대학 서울중앙병원 신경외과학교실) ;
- 김정훈 (울산대학교 의과대학 서울중앙병원 신경외과학교실) ;
- 이정교 (울산대학교 의과대학 서울중앙병원 신경외과학교실) ;
- 권병덕 (울산대학교 의과대학 서울중앙병원 신경외과학교실) ;
- 홍성관 (울산대학교 의과대학 서울중앙병원 내분비내과학교실) ;
-
이기업
(울산대학교 의과대학 서울중앙병원 내분비내과학교실) ;
- 이봉재 (울산대학교 의과대학 서울중앙병원 이비인후과학교실) ;
- 김용재 (울산대학교 의과대학 서울중앙병원 이비인후과학교실) ;
-
최충곤
(울산대학교 의과대학 서울중앙병원 방사선과학교실) ;
- 이호규 (울산대학교 의과대학 서울중앙병원 방사선과학교실)
- Received : 2001.02.07
- Accepted : 2001.05.08
- Published : 2001.05.28
Abstract
Objective : We analyzed the clinical and endocrinological results of the transsphenoidal microsurgery for ACTH secreting pituitary adenomas. Marerials and Methods : From October 1995 to August 2000, 18 patients underwent transsphenoidal microsurgery for Cushing's disease. We analyzed the surgical results of 17 patients, one patient who was previously operated from other hospital was excluded. Age of the patients were 18 to 61 years old(mean 37.7), male to female ratio was 1 : 3.3, and follow-up period was 3 to 50 months(mean 20.3). The selection of candidates for transsphenoidal exploration was based on endocrinologic criteria. Magnetic resonance imaging was the preferred radiologic test. Selective inferior petrosal sinus sampling of adrenocorticotropic hormone futher refined the diagnosis when endocrinologic and radiologic procedures were not definitive. Results : Results of the preoperative endocrinological test were : level of serum ACTH 29.4 to