Efficacy of Calcium Sulfate Pellets as Bone Graft Substitute in Lumbar Posterolateral Fusion - Preliminary Report -

요추부 후측방 유합술에서 골편대체물로서 황산칼슘의 효과에 대한 연구

  • Lee, Seung Ku (Department of Neurosurgery, School of Medicine, Hanyang University) ;
  • Kim, Choong Hyun (Department of Neurosurgery, School of Medicine, Hanyang University) ;
  • Cheong, Jin Hwan (Department of Neurosurgery, School of Medicine, Hanyang University) ;
  • Bak, Koang Hum (Department of Neurosurgery, School of Medicine, Hanyang University) ;
  • Kim, Jae Min (Department of Neurosurgery, School of Medicine, Hanyang University) ;
  • Oh, Suck Jun (Department of Neurosurgery, School of Medicine, Hanyang University)
  • 이승구 (한양대학교 의과대학 신경외과학교실) ;
  • 김충현 (한양대학교 의과대학 신경외과학교실) ;
  • 정진환 (한양대학교 의과대학 신경외과학교실) ;
  • 백광흠 (한양대학교 의과대학 신경외과학교실) ;
  • 김재민 (한양대학교 의과대학 신경외과학교실) ;
  • 오석전 (한양대학교 의과대학 신경외과학교실)
  • Received : 2001.01.29
  • Accepted : 2001.04.03
  • Published : 2001.05.28

Abstract

Objective : The authors investigated the efficacy of the calcium sulfate(OsteoSet$^{(R)}$ pellets) as an autograft extender when used to perform posterolateral lumbar fusions. Patients and Methods : Twenty patients who underwent lumbar posterolateral arthrodesis for various spinal diseases between October 1999 and March 2000 were evaluated. Arthrodesis was performed by transpedicular screw fixation and bone grafting with a mixture of autograft + calcium sulfate in a 1 : 1 ratio. At time intervals of 1, 2, 3, and 6 months, postoperative radiographs were obtained to review the resorption of calcium sulfate and the evidence of fusion. A modified Lenke scale was used to assess the status of the fusion. Results : At 2 months after operation, the average modified Lenke scale score for the OsteoSet$^{(R)}$ pellets group was 3.8. However at 6 months after operation, the average modified Lenke scale score for the OsteoSet$^{(R)}$ pellets group was 1.8. Resorption of calcium sulfate pellets was revealed in all cases at 6 months after surgery. Conclusion : It is presumed that a combination of calcium sulfate and autograft can play a role as an effective autograft extender in the posterolateral spinal fusion.

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