Journal of Korean Neurosurgical Society
- Volume 30 Issue 5
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- Pages.553-560
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- 2001
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- 2005-3711(pISSN)
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- 1598-7876(eISSN)
in vitro and in vivo Photodynamic Activity Study of U-87 Human Glioma Cell with Photofrin
실험관 및 생체내에서 U-87 교모세포종 세포주의 광역학 치료 효과에 대한 연구
- Cho, Woo Jin (Catholic Neuroscience Center, Department of Neurosurgery, The Catholic University College of Medicine) ;
- Cho, Kyung-Keun (Catholic Neuroscience Center, Department of Neurosurgery, The Catholic University College of Medicine) ;
- Ji, Cheol (Catholic Neuroscience Center, Department of Neurosurgery, The Catholic University College of Medicine) ;
- Park, Sung Chan (Catholic Neuroscience Center, Department of Neurosurgery, The Catholic University College of Medicine) ;
- Park, Hea Kwan (Catholic Neuroscience Center, Department of Neurosurgery, The Catholic University College of Medicine) ;
- Kang, Joon Ki (Catholic Neuroscience Center, Department of Neurosurgery, The Catholic University College of Medicine) ;
- Choi, Chang Rak (Catholic Neuroscience Center, Department of Neurosurgery, The Catholic University College of Medicine)
- 조우진 (가톨릭 뇌신경센터, 가톨릭대학교 의과대학 신경외과학교실) ;
- 조경근 (가톨릭 뇌신경센터, 가톨릭대학교 의과대학 신경외과학교실) ;
- 지철 (가톨릭 뇌신경센터, 가톨릭대학교 의과대학 신경외과학교실) ;
- 박성찬 (가톨릭 뇌신경센터, 가톨릭대학교 의과대학 신경외과학교실) ;
- 박해관 (가톨릭 뇌신경센터, 가톨릭대학교 의과대학 신경외과학교실) ;
- 강준기 (가톨릭 뇌신경센터, 가톨릭대학교 의과대학 신경외과학교실) ;
- 최창락 (가톨릭 뇌신경센터, 가톨릭대학교 의과대학 신경외과학교실)
- Received : 2000.07.04
- Accepted : 2001.02.20
- Published : 2001.05.28
Abstract
Objective : The objective of this study was to determine the photodynamic therapeutic response of U-87 human glioma cell in vitro as well as in the nude rat xenograft model using photofrin as photosensitizer. Material and Method : U-87 cells were cultured on 96-well culture plates, photofrin(Quadralogic Technologies Inc., Vancouver, Canada) was added into the cell culture medium at concentration of