Annals of Clinical Neurophysiology

The Korean Society of Clinical Neurophysiology (대한임상신경생리학회)
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Viral Antibody Titer Changes in Acute and Convalescent Stage of Bell's Palsy

벨마비의 급성기와 회복기에서 바이러스 항체역가의 변동

  • Suh, Sang Il (Department of Neurology, School of Medicine, Catholic University of Daegu) ;
  • Bae, Joon Soek (Department of Neurology, School of Medicine, Catholic University of Daegu) ;
  • Kim, Sung Je (Department of Neurology, School of Medicine, Catholic University of Daegu) ;
  • Kim, Tae Il (Department of Neurology, School of Medicine, Catholic University of Daegu) ;
  • Kim, Ji Eun (Department of Neurology, School of Medicine, Catholic University of Daegu) ;
  • Lee, Dong Kuck (Department of Neurology, School of Medicine, Catholic University of Daegu) ;
  • Shin, Im Hee (Department of Biostatistics, School of Medicine, Catholic University of Daegu)
  • 서상일 (대구가톨릭대학교 의과대학 신경과학교실) ;
  • 배준석 (대구가톨릭대학교 의과대학 신경과학교실) ;
  • 김성제 (대구가톨릭대학교 의과대학 신경과학교실) ;
  • 김태일 (대구가톨릭대학교 의과대학 신경과학교실) ;
  • 김지언 (대구가톨릭대학교 의과대학 신경과학교실) ;
  • 이동국 (대구가톨릭대학교 의과대학 신경과학교실) ;
  • 신임희 (대구가톨릭대학교 의과대학 의학통계학교실)
  • Published : 2001.07.30
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Abstract

Background : Bell's palsy(BP) is defined as an idiopathic peripheral facial paralysis of acute onset, accounting for more than 50% of all cases of facial paralysis. Different theories on the etiology of BP have been proposed. Herpes simplex virus-1(HSV) has been the most suspicious causative agent, but varicella zoster virus(VZV) also is suspected. Objectives : We evaluated the serological changes of IgG and IgM titer of HSV and VZV to know the causative agent of BP. Materials and Methods : Subjects consisted of 35 patients who developed acute idiopathic unilateral facial palsy(16 men and 19 women from 9 to 78 years old) within a week of onset. We took the serum of the acute and convalescent stages, respectively. Serum IgG and IgM titer of HSV and VZV were measured in acute and convalescent stages by EIA method. Results : Only the HSV IgG titer showed statistically significant elevation in the convalescent stage(p=0.0291). Others did not show any significant change between the acute and convalescent stage. Conclusion : We concluded that HSV may be related to the causative agent of BP.

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