Journal of Acupuncture Research

Korean Acupuncture & Moxibustion Medicine Society (대한침구의학회)
권호 표지

The Effect of Juglandis Semen Aquacupuncture on Urine Concentrating Defect in Glycerol-induced Acute Renal Failure

호도약침(胡桃藥鍼)이 Glycerol에 의한 급성신부전(急性腎不全) 유발(誘發)시 요농축능(尿濃縮能)의 장애(障碍)에 대한 영향(影響)

  • Lee, Byung-Hoon (Department of Acupuncture & Moxibustion, College of Oriental Medicine, Dong-Eui University) ;
  • Seo, Jung-Chul (Department of Acupuncture & Moxibustion, College of Oriental Medicine, Dong-Eui University) ;
  • Youn, Hyoun-Min (Department of Acupuncture & Moxibustion, College of Oriental Medicine, Dong-Eui University) ;
  • Song, Choon-Ho (Department of Acupuncture & Moxibustion, College of Oriental Medicine, Dong-Eui University) ;
  • Ahn, Chang-Beohm (Department of Acupuncture & Moxibustion, College of Oriental Medicine, Dong-Eui University) ;
  • Jang, Kyung-Jeon (Department of Acupuncture & Moxibustion, College of Oriental Medicine, Dong-Eui University)
  • 이병훈 (동의대학교 한의과대학 침구경혈학교실) ;
  • 서정철 (동의대학교 한의과대학 침구경혈학교실) ;
  • 윤현민 (동의대학교 한의과대학 침구경혈학교실) ;
  • 송춘호 (동의대학교 한의과대학 침구경혈학교실) ;
  • 안창범 (동의대학교 한의과대학 침구경혈학교실) ;
  • 장경전 (동의대학교 한의과대학 침구경혈학교실)
  • Received : 2001.05.04
  • Accepted : 2001.05.19
  • Published : 2001.06.20
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Abstract

Objective : The present study was carried out to determine if Juglandis Semen Aquacupuncture(JSA) exerts beneficial effect against the urine concentrating defect induced by glycerol injection in rabbits. Methods : In order to test the effect of JSA, rabbits were acupunctured with $0.5m{\ell}$ of 1%JSA for 7days at both sides of $Sh{\grave{e}}ns{\bar{u}}$(BL23) before the glycerol injection. The other animals were pretreated with an equal volume of saline instead of JSA. Results : The urine flow was reduced, but the urine osmolality was significantly lower than the basal period in glycerol-injected animals, indicating that glycerol causes the urine concentrating defect. The fractional excretion of Na and K was increased in glycerol-treated animals. The Free-water clearance and fractional water excretion(V/GFR) were increased in animals treated with glycerol. Conclusion : These results indicate that glycerol injection resulted an impairment in the urine concentrating ability in rabbits. Such changes were prevented by JSA. JSA may be used as a method to treat and prevent glycerol-induced acute renal failure.

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