Journal of Preventive Medicine and Public Health

  • 제34권2호
  • /
  • Pages.149-156
  • /
  • 2001
  • /
  • 1975-8375(pISSN)
  • /
  • 2233-4521(eISSN)
대한예방의학회 (The Korean Society for Preventive Medicine)
권호 표지

관상동맥질환 위험요인 구명을 위한 코호트내 환자-대조군 연구

A Nested Case Control Study on Risk Factors for Coronary Heart Disease in Korean

  • 김기순 (조선대학교 의과대학 예방의학교실) ;
  • 박종 (조선대학교 의과대학 예방의학교실) ;
  • 박종구 (연세대학교 원주의과대학 예방의학교실) ;
  • 김춘배 (연세대학교 원주의과대학 예방의학교실) ;
  • 천병렬 (경북대학교 의과대학 예방의학교실) ;
  • 이태용 (충남대학교 의과대학 예방의학교실) ;
  • 이강숙 (가톨릭대학교 의과대학 예방의학교실) ;
  • 이덕희 (고신대학교 의과대학 예방의학교실) ;
  • 고광욱 (고신대학교 의과대학 예방의학교실) ;
  • 지선하 (연세대학교 보건대학원) ;
  • 서일 (연세대학교 의과대학 예방의학교실) ;
  • 류소연 (조선대학교 의과대학 예방의학교실)
  • Kim, Ki-Soon (Department of Preventive Medicine, College of Medicine, Chosun University) ;
  • Park, Jong (Department of Preventive Medicine, College of Medicine, Chosun University) ;
  • Park, Jong-Ku (Department of Preventive Medicine, Yonsei University Wonju College of Medicine) ;
  • Kim, Chun-Bae (Department of Preventive Medicine, Yonsei University Wonju College of Medicine) ;
  • Chun, Byung-Yeol (Department of Preventive Medicine and Public Health, School of Medicine, Kyungpook National University) ;
  • Lee, Tae-Yong (Department of Preventive Medicine, College of Medicine, Chungnam National University) ;
  • Lee, Kang-Sook (Department of Preventive Medicine, Catholic University Medical College) ;
  • Lee, Duk-Hee (Department of Preventive Medicine, College of Medicine, Kosin University) ;
  • Koh, Kwang-Wook (Department of Preventive Medicine, College of Medicine, Kosin University) ;
  • Jee, Sun-Ha (Graduate School of Health Science and Management, Yonsei University) ;
  • Suh, Il (Department of Preventive Medicine and Public Health, Yonsei University College of Medicine) ;
  • Ryu, So-Yeon (Department of Preventive Medicine, College of Medicine, Chosun University)
  • 발행 : 2001.06.01
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초록

Objective : To elucidate risk factors for coronary heart diseases among Korean males. Methods : A nested case control study was conducted among a Korea Medical Insurance Cooperation(KMIC) cohort composed of 108,802 males. The eases included 246 male patients who were admitted to hospital due to coronary heart diseases from 1993 to 1997 (120-25 by ICD) and whose diagnosis was confirmed by the protocol by WHO MONICA Project(1994). The control group was composed of 483 patients selected by frequency matching considering age and resident area from an inpatient care group without coronary heart disease during the same period. For study cases and the controls, the results of a health check-up in 1990 and a questionnaire on life style in 1992 were received through the KMIC. Some additional information was collected by telephone interviews during October 1999. Results : Multiple logistic regression analysis showed that the odds ratio(OR) of coronary heart diseases among past smokers and current smokers as compared to non-smokers were 1.94(95% CI : 1.14-3.31) and 2.20(55% CI : 1.35-3.59), respectively. The OR among persons who drank 4 cups or more of caffeinated beverages such as coffee or tea daily as compared to persons who drank one cup for 2-3 days was 2.50(95% CI : 1.07-6.12). The OR among persons with high normal BP and stage 3 hypertension against normotension were 2.51 (95% CI : 1.44-4.37) and 5.08(95% CI : 2.38-10.84). The OR among persons whose blood cholesterol were 240 mg/dL or mere against lower than 200mg/dL was 2.24(95% CI : 1.43-3.49). Conclusion : Smoking, drinking of excessive caffeinated beverages, hypertension and high blood cholesterol were proven to be significant risk factors for coronary heart diseases among Korean males.

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