The Effect of Cold Application on Ischemia-Reperfusion Injury to Quadriceps Femoris Muscle of the Rats

한냉이 흰쥐 대퇴사두근의 허혈 - 재관류 후 SOD 발현에 미치는 영향

  • Choi, Jin-Ho (Department of physical Therapy, Yeongdong Junior College) ;
  • Nam, Ki-Won (Major in Physical Therapy, Dept of Rehabilitation Science, Graduate School, Taegu University) ;
  • Kim, Jin-Sang (Department of physical Therapy, College of Rehabilitation Science, Taegu University)
  • 최진호 (영동전문대학 물리치료과) ;
  • 남기원 (대구대학교 대학원 재활과학과 물리치료) ;
  • 김진상 (대구대학교 재활과학대학 물리치료학과)
  • Published : 2001.07.21

Abstract

The purpose of this study was to investigate the effect of cold application on ischemia-reperfusion injury to quadriceps fomoris muscle of the hindlimbs of the rats. Nine weeks old male Sprague-Dawley white rats were divided into three groups : 1) control(only ischemia-reperfusion), 2) cold application before reperfusion(PreCold), 3) cold application after reperfusion(PostCold). All groups were 30 minute, 1 hour, 3 hours reperfusion after 2 hours ischemia with clamping abdominal artery, and investigate superoxide dismutase(SOD) immunohistochemical reaction for quadriceps femoris muscle of right hindlimb. SOD immunohistochemical reaction of experimental groups were more than the control group. Especially, SOD immunohistochemical reaction of PreCold were less than the PostCold.

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