The Concentrations and TEQ Levels of PCDFs and PCDDs in Human Adipose Tissue and First Breast Milk of Korean

체지방 조직 및 초유중에 잔류되어 있는 다이옥신 함유도에 관한 연구

  • Kim, Yunje (Doping Control Center, Korea Institute of Science and Technology) ;
  • Lee, Sun Young (Doping Control Center, Korea Institute of Science and Technology) ;
  • Han, Soon Young (National Institute of Toxicological Research, Korea Food and Drug Administration) ;
  • Park, Kui Lea (National Institute of Toxicological Research, Korea Food and Drug Administration) ;
  • Kil, Kwang Sup (National Institute of Toxicological Research, Korea Food and Drug Administration) ;
  • Yang, Kyu Hwan (National Institute of Toxicological Research, Korea Food and Drug Administration) ;
  • Kim, Eun Kyung (Department of Biotechnology & Bioinformatics Chungbuk Provincial University of Science and Technology) ;
  • Kim, Myungsoo (Doping Control Center, Korea Institute of Science and Technology)
  • 김연제 (한국과학기술연구원 도핑콘트롤센터) ;
  • 이선영 (한국과학기술연구원 도핑콘트롤센터) ;
  • 한순영 (식품 의약품 안전청 국립 독성 연구소) ;
  • 박귀례 (식품 의약품 안전청 국립 독성 연구소) ;
  • 길광섭 (식품 의약품 안전청 국립 독성 연구소) ;
  • 양규환 (식품 의약품 안전청 국립 독성 연구소) ;
  • 김은경 (충북과학대 생명정보학과) ;
  • 김명수 (한국과학기술연구원 도핑콘트롤센터)
  • Received : 2001.06.12
  • Published : 2001.12.25

Abstract

The concentrations and TEQ levels of PCDFs/PCDDs in human aipose tissue and first breast milk were analyzed by high resolution gas chromatography/high resolution mass spectrometry. The human adipose tissue samples measured in this study have been collected at hospital in Seoul. The total concentration and TEQ level of PCDFs were showed 5.812 pg/g and 1.485 pgTEQ/g. The total concentration and TEQ level of PCDDs were showed 26.648 pg/g and 1.176 pgTEQ/g, respectively. This paper also reported dioxin levels in 20 breast milks of Korean mothers from hospital in Seoul National University. Total concentration and TEQ levels of PCDFs were showed 7.019 pg/mL and 0.177 pgTEQ/mL, respectively. Total concentrations and TEQ levels of PCDDs were showed 14.224 pg/mL and 0.693 pgTEQ/mL, respectively. According to the contribution of dioxin congeners in samples, PCDDs was higher than PCDFs. And OCDD had the highest concentration.

우리 나라 사람들의 체지방 조직과 초유중에서, 다이옥신의 잔류 농도를 HRGC/HRMS를 이용하여 동위원소희석법으로 측정하였다. 체지방 조직 시료는 서울에 있는 모병원에서 채취하였으며, 체지방 조직에서의 PCDFs의 총농도와 TEQ 농도는 각각 5.812 pg/g, 1.485 pgTEQ/g 이었고, PCDDs의 총농도와 TEQ 농도는 각각 26.648 pg/g, 1.176 pgTEQ/g 이었다. 서울대학 병원으로부터 받은 산모 20명의 초유에 함유된 다이옥신의 잔류농도는 PCDFs의 총 농도가 7.019 pg/mL, TEQ 농도로 환산하면 0.177 pgTEQ/mL 이었고, PCDDs의 총 농도와 TEQ 농도는 각각 14.224 pg/mL, 0.693 pgTEQ/mL이었다. 체지방 조직과 모유에서의 다이옥신 이성질체들의 분포는 PCDDs가 PCDFs보다 상대적으로 높게 나타났으며, 그중 OCDD가 가장 높은 농도로 포함되어 있다.

Keywords

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