Bulletin of the Korean Chemical Society

  • 제22권4호
  • /
  • Pages.372-374
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  • 2001
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  • 0253-2964(pISSN)
  • /
  • 1229-5949(eISSN)
대한화학회 (Korean Chemical Society)
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Unsual Cytotoxic Phenethylamides form Xenerhabdus nemetophilus

  • 발행 : 20010400
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초록

Three simple carboxamides incorporating the phenethylamine moiety have been isolated from strain XR-NC of a symbiotic bacterium Xenorhabdus nematophilus. Their structures were identified by spectroscopic data and synthesis. The compounds exhibited significant cytotoxicities against human cancer-cell line, viz. the gastric adenocarcinoma, colon adenocarcinoma and lung adenocarcinoma.

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참고문헌

  1. J. Gen. Microbiol. v.128 Akhurst, R. J.
  2. J. Chem. Ecol. v.7 Paul, V. J.;Frautschy, S.;Fenical, W.;Nealson, K. H. J.
  3. Microbiol. Rev. v.60 Frost, S.;Nealson, K.
  4. Appl. Environ. Microbiol. v.60 Maxwell, P. W.;Chen, G.l;Webster, J. M.;Cunphy, G. B.
  5. Bio. Control v.4 Chen, G. Dunphy, G. B.;Webster, J. M.
  6. J. Microbiol. v.43 Li, J.;Chen, G.;Webster;J. M. Can
  7. J. Nat. Prod. v.59 Li, J.;Chen, G.;Webster, J. M.
  8. J. Chem. Ecol. v.7 Paul, V. J.;Frautschy, S.;Fenical, W.;Nealson, K. H.
  9. J. Nat. Prod. v.58 Li, J.;Chen, G.;Webster, J. M.;Czyzewska, E.
  10. J. Nat. Prod. v.54 Mclnerney, B. V.;Gregson, R. P.;Lacey, M. J.;Akhurst, R. J.;Lyons, G. R.;Rhides, S. H.;Smith, D. R.;Enelhardt, L. M.;White, A. H.
  11. Appl. Environ. Microbiol. v.54 Richardson, W. H.;Schmidt, T. M.lnealson, K. H.
  12. J. Nat. Prod. v.54 Mclnerney, B. V.;Taylor, W. C.;Lacey, M. J.;Akhurst, R. J.;Gregson, B. V.
  13. Biotechnol. Bioprocess Eng. v.4 Park, S. H.;Yu, Y. S.
  14. Biotechnol. Bioprocess Eng. v.5 Ryu, K. G.;Bae, J. S.;Yu, Y. S.;Park, S. H.
  15. Br. J. Cancer v.56 Twentyman, P.;Luscombe, M.
  16. J. Org. Chem. v.13 Huntress, E. H.;Shaw, E. N.
  17. J. Med. Chem. v.22 Ginos, J. Z.;Stevens, J. M.lNichols, D. E.
  18. Shima, H. Jpn. Kokai Tokyo Koho JP 0503,792, Compound 3 was only reported from the Culture broth of Bacilus BN-1

피인용 문헌

  1. Isolation and Synthesis of Tryptamine Derivatives from a Symbiotic Bacterium Xenorhabdus nematophilus PC vol.24, pp.5, 2001, https://doi.org/10.5012/bkcs.2003.24.5.623
  2. Bacterial Insecticidal Toxins vol.30, pp.1, 2004, https://doi.org/10.1080/10408410490270712
  3. Effect of amino acids containing sulfur on dithiolopyrrolone antibiotic productions by Saccharothrix algeriensis NRRL B-24137 vol.100, pp.2, 2006, https://doi.org/10.1111/j.1365-2672.2005.02762.x
  4. Clonal variation in Xenorhabdus nematophila virulence and suppression of Manduca sexta immunity vol.9, pp.3, 2007, https://doi.org/10.1111/j.1462-5822.2006.00815.x
  5. Effect of culture conditions on antifouling compound production of a sponge-associated fungus vol.74, pp.6, 2007, https://doi.org/10.1007/s00253-006-0780-0
  6. The Diversity of Insect-bacteria Interactions and its Applications for Disease Control vol.25, pp.1, 2001, https://doi.org/10.5661/bger-25-203
  7. Engineered Thiomarinol Antibiotics Active against MRSA Are Generated by Mutagenesis and Mutasynthesis of Pseudoalteromonas SANK73390 vol.123, pp.14, 2011, https://doi.org/10.1002/ange.201007029
  8. Engineered Thiomarinol Antibiotics Active against MRSA Are Generated by Mutagenesis and Mutasynthesis of Pseudoalteromonas SANK73390 vol.50, pp.14, 2001, https://doi.org/10.1002/anie.201007029
  9. Cytotoxic Fatty Acid Amides from Xenorhabdus vol.12, pp.13, 2001, https://doi.org/10.1002/cbic.201100223
  10. Investigations of the marine flora and fauna of the Fiji Islands vol.29, pp.12, 2001, https://doi.org/10.1039/c2np20055d
  11. Identification of Two Putative Acyltransferase Genes Potentially Implicated in Dithiolopyrrolone Biosyntheses in Saccharothrix algeriensis NRRL B-24137 vol.173, pp.3, 2001, https://doi.org/10.1007/s12010-014-0896-0
  12. Defensive symbioses of animals with prokaryotic and eukaryotic microorganisms vol.32, pp.7, 2001, https://doi.org/10.1039/c5np00010f