한국가축번식학회지 (Korean Journal of Animal Reproduction)
- 제25권3호
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- Pages.237-242
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- 2001
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- 1226-5284(pISSN)
외래유전자의 게놈내 삽입에 있어서 DNA형태가 미치는 영향
Effect of DNA Conformation on Genomic Integration of Transgenes and Its Implications on Integration Mechanism
- 강용국 (한국생명공학연구원 동물발생공학 연구실) ;
- 박정선 (한국생명공학연구원 동물발생공학 연구실) ;
- 이철상 (한국생명공학연구원 동물발생공학 연구실) ;
- 한용만 (한국생명공학연구원 동물발생공학 연구실) ;
- 이경광 (한국생명공학연구원 동물발생공학 연구실)
- Kang, Y.K. (Animal Developmental Biotechnology Laboratory, Korea Research Institute of Bioscience and Biotechnology) ;
- Park, J.S. (Animal Developmental Biotechnology Laboratory, Korea Research Institute of Bioscience and Biotechnology) ;
- Lee, C.S. (Animal Developmental Biotechnology Laboratory, Korea Research Institute of Bioscience and Biotechnology) ;
- Han, Y.M. (Animal Developmental Biotechnology Laboratory, Korea Research Institute of Bioscience and Biotechnology) ;
- Lee, K.K. (Animal Developmental Biotechnology Laboratory, Korea Research Institute of Bioscience and Biotechnology)
- 발행 : 2001.09.01
초록
본 실험실에서는 최근에 SINE계 B
We recently demonstrated that both linear- and supercoil-form B1/B2 SINE (short interspersed elements) sequences could increase an integration frequency of a reporter gene in preimplatation mouse embryos. In those reports, when either a control or SINE-flanked DNA was separately applied to microinjection, the proportions of
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