Archives of Pharmacal Research

The Pharmaceutical Society of Korea (대한약학회)
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A New Naphthoquinone from Pyrola japonica

  • Lee, Sang-Myung (Korea Research Institute of Bioscience and Biotechnology) ;
  • An, Ren-Bo (College of Pharmacy, Chungnam National University) ;
  • Min, Byung-Sun (Korea Research Institute of Bioscience and Biotechnology) ;
  • Na, Min-Kyun (College of Pharmacy, Chungnam National University) ;
  • Lee, Choong-Hwan (Korea Research Institute of Bioscience and Biotechnology) ;
  • Kang, Shin-Jyung (Department of Life Science, Joongbu University) ;
  • Maeng, Hack-Young (Department of Life Science, Joongbu University) ;
  • Bae, Ki-Hwan (College of Pharmacy, Chungnam National University)
  • Published : 2001.12.01
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Abstract

A new naphthoquinone, 5,8-dihydro-2,7-dimethyl-[1,4]naphthoquinone (1), which was named 5,8-dihysrochimaphilin, isolated from an ethyl acetate soluble fraction from the root of Pyrola japonica, together with chimaphilin (2). Compound 1 was transformed rapidly to 2 upon exposure to air by HPLC analysis. This fact supported that chimaphilin (2) may be an artifact from 1 .

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References

  1. Yakhak Hoeji v.40 Isolation and evaluation of an antitumor constituent from Pyrolae Herba Bae,K.;Kim,H.M.;Lee,S.
  2. Chem. Pharm. Bull. v.40 Platelet aggregation inhibitory and inotropic constituents in Pyrolae Herba Kagawa,K.;Tokura,K.;Uchida,K.;Kakushi,H.;Shike,T.;Nakai,H.
  3. Chem. Pharm. Bull. v.33 Isolation and identification of anti-inflammatory and analgesic principles from the whole herb of Pyrola rotundifolia L Kosuge,T.;Yokota,M.;Sugiyma,K.;Mure,T.;Yamazawa,H.;Yamamoto,T.
  4. Zhongcaoyao v.19 Chemical constituents of the Chinese Pyrola Wang,X.;Zhang,J.;Cao,A.;Ma,G.;Li,H.;Yang,B.