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The Pharmaceutical Society of Korea (대한약학회)
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One-pot Synthesis of Cinnamylamines with Various Protecting Groups from Cinnamyl Ethers

  • Jung, Young-Hoon (Organic ＆ Medicine Chemistry Laboratory, College of Pharmacy, Sungkyunkwan University) ;
  • Kim, Ji-Duck (Organic ＆ Medicine Chemistry Laboratory, College of Pharmacy, Sungkyunkwan University)
  • Published : 2001.10.01
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Abstract

The reaction of various alkyl cinnamyl ethers with CSI afforded the corresponding cinnamylamines with various protecting groups, such as -NHMoc, -NHiPoc, -NHCbz, -NHPnz, -NHTroc and -NHAloc. In the case of cinnamyl t-butyl ether and cinnamyl p-methoxybenzyl ether, the corresponding cinnamyl carbamates were formed via a different reaction pathway from the above.

Keywords

References

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