Triterpenes and Phenolic Constituents from Viscum album L.

상기생의 트라이테르펜 및 페놀성 성분

  • Published : 2001.12.01

Abstract

The photochemical study of Viscum album (Loranthaceae) led to the isolation of twelve compounds, lupeol (1), betulonic acid (2), betulinic acid (3), terminic acid (4), ursolic acid (5), $\beta$-sitosterol (6), $\alpha$- spinasterol (7), oleanolic acid (8) , 5-hydroxy-1- (4′-hydoxyphenyl) -7- (4"-hydroxyphenyl) -hepta-1- en-3-on (9), 2′-hydroxy -4′, 6′- dimethoxychalcone -4-O-glycoside (10) ,2′-hydroxy-4′, 6′-dimethoxychalcone -4-O- [apiosal(1longrightarrow12)]glucoside (11) and syringin (12). Their structures were established by chemical and spectroscopic methods. The cytotoxicity of the isolated compounds was evaluated by sulforhodamine B assay against five cultured human tumor cell lines.

Keywords

References

  1. 한국의 약용식물 배기환
  2. Chem. Pharm. Bull. v.35 no.3292 Studies on the constituents of the European mistletoe, Viscum album L Fukunaga, T.;Kajikawa, I.;Nishiya, K.;Watanabe, Y.;Takeya, K.
  3. J. Biol. Chem. v.267 no.2372 Ligand binding characteristics of the major mistletoe lectin Lee, R. T.;Gabius, H. J.;Lee, Y. C.
  4. Oncology. v.43 no.Suppl 1 Structures and properties of polysaccharides from Viscum album Jordan, E.;Wagner, H.
  5. Oncology. v.43 no.Suppl 1 Recent studies on the anticancer activities of mistletoe (Viscum album) and its alkaloids Khwajawa, T. A.;Dias, C. B.;Pentecost, S.
  6. J. Natl. Cancer Inst. v.82 no.1107 New colorimetric cytotoxicity assay for anticancer-drug screening Skehan, P.;Storeng, R.;Scudiero, D.;Monks, A.;McMahon, J.;Vistica, D.;Warren, J. T.;Bokesch, H.;Kenney, S.;Boyd, M. R.
  7. Phytochemistry v.19 no.2707 Triterpenes in Organ pipe cactus Kircher, H. W.
  8. Phytochemistry v.22 no.1828 3-Oxo-6b-hydroxyolean-18-en-oic acid from Orthopterygium huancuy Gonzalez, A. G.;Amaro, J.;Fraga, B. M.;Luis, J.
  9. Phytochemistry v.26 no.1107 Pentacyclic triterpenoids from Prunella vulgaris Kojima, H.;Tominaga, H.;Sato, S.;Ogura, H.
  10. Phytochemistry v.22 no.993 Structure of terminic acid, a dihydroxytriterpene carboxylic acid from Terminalia arjuna Anjaneyulul, A. S. R.;Rama Prasad, A. V.
  11. Handbook of natural products data v.2 Pentacyclic triterpenoids Ahmad, V. U.;Rahman, A. U.
  12. Phytochemistry v.37 no.1517 13C NMR spectra of pentacyclic triterpenoids-a complilation and some salient features Mahato, S. B.;Kundu, A. P.
  13. Phytochemistry v.26 no.715 Triterpenoids from Eucalyptus periniana cultured cells Furuya, T.;Orihara, Y.;Hayashi, C.
  14. Analysis of sterols Goad, L. J.
  15. Handbook of natural products data v.2 Pentacyclic triterpenoids Ahmad, V. U.;Rahman, A. U.
  16. Phytochemistry v.47 no.1117 Stilbenes, monoterpenes, diarylheptanoids, labdanes and chalcones from Alpinia katsumadai Ngo, K. S.;Brown, G. D.
  17. Phytochemistry v.31 no.3307 NMR spectroscopy in the structural elucidation of oilgosaccharides and glycoside Agrawal, P.k.